| Type | Description |
|---|---|
| Definition | mannose-6-phosphate receptor, cation dependent |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 12:59:00 | Monochorionic twins with selective fetal growth restriction: insight from placental whole-transcriptome analysis. | 32437666 |
| 2020-03-21 11:22:00 | The co-localization of M6PR and of GCC2 with ASOs is influenced by the PS modifications, which have been shown to enhance the affinity of ASOs for proteins, suggesting that localization of these proteins to LEs is mediated by ASO-protein interactions. Reduction of M6PR levels also decreased PS-ASO activity in mouse cells and in livers of mice treated subcutaneously with PS-ASO, indicating a conserved mechanism. | 31840180 |
| 2019-10-05 11:13:00 | Mannose-6-phosphate receptor: a novel regulator of T cell immunity. | 29769659 |
| 2019-02-09 10:34:00 | Results suggest that, in hormone-responsive breast cancer cells, CD-MPR and cathepsin D are distributed together, and that their expression and distribution are influenced by estradiol. These findings strongly support the involvement of the CD-MPR in the pro-enzyme transport in MCF-7 cells, suggesting the participation of this receptor in the procathepsin D secretion previously reported in breast cancer cells. | 30086159 |
| 2018-09-15 10:56:00 | Most rotavirus strains require the cation-independent mannose-6-phosphate receptor, sortilin-1, and cathepsins to enter cells. | 29275103 |
| Type | IDs |
|---|---|
| Synonymous | CD-M6PR, CD-MPR, MPR 46, MPR-46, MPR46, SMPR |
| Gene |
UniProtKB-ID:
MPRD_HUMAN,
F5GX30_HUMAN
UniprotKB:
P20645,
F5GX30
UniParc:
UPI000004E7FC,
UPI0000229053
EMBL:
M16985,
AC006581,
X56255,
BC024206,
X56254,
AK291143,
CH471116,
X56256,
X56257
Ensembl:
ENSG00000003056
KO:
hsa:4074
|
| Nucleutide sequences |
EMBL-CDS:
EAW88598.1,
AAH24206.1,
CAB94715.1,
EAW88597.1,
BAF83832.1,
EAW88596.1,
EAW88599.1,
AAA59542.1
Ensembl_TRS:
ENST00000000412,
ENST00000536844
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000000412,
ENSP00000440488
RefSeq:
NP_002346.1,
NP_001193953.1,
XP_005253433.1
|
| Others |
UniRef100:
UniRef100_P20645,
UniRef100_F5GX30
UniRef90:
UniRef90_P20645,
UniRef90_F5GX30
UniRef50:
UniRef50_P20645,
UniRef50_A0A2I3MKP3
UniGene:
Hs.134084,
Hs.744902
CCDS:
CCDS8598.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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