| Type | Description |
|---|---|
| Definition | asterless |
| Date | Results | Publications |
|---|---|---|
| 2019-09-07 10:49:00 | By halfway through pupal life, the centriole number decreases and structural defects, ranging from being incomplete or lacking B-tubules, are detected. Asl, Ana1 and Sas-4 are still present, suggesting that the centriole integrity does not depend on these proteins. | 29361550 |
| 2017-08-12 10:34:00 | ana1 mutants lack detectable centrosomes in vivo, that Ana1 is irreversibly incorporated into centrioles during their assembly and appears to play a more important role in maintaining Asl at centrioles than in initially recruiting Asl to centrioles...the N-terminal region of Ana1 (amino acids 1-935) is required to target Ana1 to centrioles through a direct interaction with Cep135, whereas the C-terminal region of Ana1. | 27206860 |
| 2015-09-26 21:21:00 | Asl is not incorporated into daughter centrioles as they assemble during S phase but is only incorporated once mother and daughter separate at the end of mitosis. | 24835456 |
| 2015-05-02 12:57:00 | Asl not only targets Plk4 to centrioles but also modulates Plk4 stability and activity, explaining the ability of overexpressed Asl to drive centriole amplification. | 25688134 |
| 2013-06-29 12:16:00 | Data indicate that interphase centrioles are closely associated with Sas-4, Spd-2, Polo kinase, Pericentrin-like protein (Dplp), Asterless (Asl), Plk4 kinase, Centrosomin (Cnn) and gamma-tubulin. | 22977736 |
| Type | IDs |
|---|---|
| Synonymous | ASL, Asl, CG2919, Cep152, Dmel\CG2919, mecD, sdu |
| Gene |
UniProtKB-ID:
Q9VNE4_DROME
UniprotKB:
Q9VNE4
UniParc:
UPI00001B98D7
EMBL:
AE014297,
BT010112
EnsemblGenome:
FBgn0261004
KO:
dme:Dmel_CG2919
|
| Nucleutide sequences |
EMBL-CDS:
AAF51993.2,
AAQ22581.1
Gene_ORFName:
CG2919,
Dmel_CG2919
EnsemblGenome_TRS:
FBtr0078743
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0078392
RefSeq:
NP_649557.2
|
| Others |
UniRef100:
UniRef100_Q9VNE4
UniRef90:
UniRef90_Q9VNE4
UniRef50:
UniRef50_Q9VNE4
UniGene:
Dm.11407
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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