| Type | Description |
|---|---|
| Definition | APEX nuclease (multifunctional DNA repair enzyme) 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 12:25:00 | Knock-down of Apex1 not only resulted in reduction of expression of several major proteins in the BER pathway (Polb and Ogg1), and it also resulted in maldistribution and loss of four key brain transcription factors (fezf2, otx2, egr2a, and pax2a), leading to abnormal brain development. | 31024003 |
| Type | IDs |
|---|---|
| Synonymous | APEN, apex1a, hm:zehn1532, wu:fc13d11, zap1, zgc:66204 |
| Gene |
UniProtKB-ID:
A0A0R4IWF9_DANRE,
A0A2R9YJQ0_DANRE,
F1QTR9_DANRE
UniprotKB:
A0A0R4IWF9,
A0A2R9YJQ0,
F1QTR9
UniParc:
UPI000383784D,
UPI0003836430,
UPI0000438300
EMBL:
BX323558
Ensembl:
ENSDARG00000045843
KO:
dre:406730
|
| Nucleutide sequences |
Ensembl_TRS:
ENSDART00000163850,
ENSDART00000180644,
ENSDART00000067374,
ENSDART00000129398
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000138791,
ENSDARP00000156404,
ENSDARP00000067373,
ENSDARP00000110718
RefSeq:
NP_998586.2,
NP_001315508.1,
NP_001315507.1,
NP_001315509.1,
XP_021330658.1
|
| Others |
UniRef100:
UniRef100_F1QTR9,
UniRef100_A0A0R4IWF9
UniRef90:
UniRef90_A0MTA1
UniRef50:
UniRef50_A0MTA1
UniGene:
Dr.20170
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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