| Type | Description |
|---|---|
| Definition | LYL1 basic helix-loop-helix family member |
| Date | Results | Publications |
|---|---|---|
| 2019-11-16 12:06:00 | Repression of LYL1 contributes to t(8;21) leukemic cell differentiation. | 30755707 |
| 2018-12-22 10:15:00 | Despite not being identified as an independent prognostic factor in UCEC, LYL1 gene amplification is associated with other poor prognostic factors and correlated with upregulation of cancer-related pathways. | 29716549 |
| 2014-04-18 13:13:00 | In t(8;21) leukemia cells, LYL1 functions as a component of the stable AML1-ETO-containing transcription factor complex (AETFC). The AETFC components cooperatively regulate gene expression and contribute to leukemogenesis. | 23812588 |
| 2013-05-18 11:37:00 | Transcriptional regulators cooperate to establish or maintain primitive stem cell-like signatures in leukemic cells. | 23327922 |
| 2011-02-26 10:58:00 | LYL1 degradation is directed by a N-terminal PEST rich site in a phosphorylation-independent manner. | 20844761 |
| Type | IDs |
|---|---|
| Synonymous | bHLHa18 |
| Gene |
UniProtKB-ID:
LYL1_HUMAN
UniprotKB:
P12980
UniParc:
UPI000013D576
EMBL:
AC005546,
M22637,
M22638,
BC002796,
AC007787
Ensembl:
ENSG00000104903
KO:
hsa:4066
|
| Nucleutide sequences |
EMBL-CDS:
AAA88085.1,
AAA88084.1,
AAC33149.1,
AAA92488.1,
AAH02796.2
Ensembl_TRS:
ENST00000264824
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000264824
RefSeq:
NP_005574.2
|
| Others |
UniRef100:
UniRef100_P12980
UniRef90:
UniRef90_P12980
UniRef50:
UniRef50_P12980
UniGene:
Hs.46446,
Hs.728534
CCDS:
CCDS12292.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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