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40653 PEK

40653

PEK

pancreatic eIF-2alpha kinase

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition pancreatic eIF-2alpha kinase

研究结论

Date Results Publications
2020-11-21 13:16:00 PERK-Mediated eIF2alpha Phosphorylation Contributes to The Protection of Dopaminergic Neurons from Chronic Heat Stress in Drosophila. 32013014
2019-02-09 11:27:00 X-box binding protein 1 overexpression at an early stage reversed Abeta-induced early death without affecting learning performance in the Abeta42 transgenic flies. PERK activation was determined to only enhance Abeta-induced learning deficits. 29427089
2018-12-22 11:35:00 PERK and GCN2 act on FOXO to potentiate FOXO activity which has been implicated in the development and progression of a variety of diseases. 30043468
2016-04-30 10:42:00 We show that the PKR-like ER kinase (PERK) integrates both cell-autonomous and non-autonomous endoplasmic reticulum stress stimuli to induce intestinal stem cell proliferation. 25945494

名称对应

Type IDs
Synonymous CG2087, DPERK, DmPEK, Dmel\CG2087, DpERK, PERK, Pek, Perk, dPERK, dPerk, pERK, pek, perk
Gene
UniProtKB-ID: E2AK3_DROME, A0A0B4KGJ5_DROME, A0A0B4KG56_DROME
UniprotKB: Q9NIV1, A0A0B4KGJ5, A0A0B4KG56
UniParc: UPI000293FBCB, UPI0000007415, UPI0002940781
EMBL: AY094831, AF193340, AJ313085, AE014297
EnsemblGenome: FBgn0037327
KO: dme:Dmel_CG2087
Nucleutide sequences
EMBL-CDS: CAC85207.1, AAF52028.2, AAM11184.1, AAF61200.1, AGB95665.1, AGB95666.1
Gene_ORFName: CG2087, CG2087, Dmel_CG2087, Dmel_CG2087, CG2087
EnsemblGenome_TRS: FBtr0078770, FBtr0330026, FBtr0330027
Protein sequencees
EnsemblGenome_PRO: FBpp0078417, FBpp0303059, FBpp0303060
RefSeq: NP_001262282.1, NP_649538.1, NP_001262283.1
Others
UniRef100: UniRef100_A0A0B4KGJ5, UniRef100_Q9NIV1, UniRef100_A0A0B4KG56
UniRef90: UniRef90_Q9NIV1
UniRef50: UniRef50_Q9NIV1
UniGene: Dm.3303

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