leg1.2 - liver-enriched gene 1, tandem duplicate 2-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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406484 leg1.2

基因描述

Type	Description
Definition	liver-enriched gene 1, tandem duplicate 2

研究结论

Date	Results	Publications
2016-07-30 11:10:00	Leg1 plays a unique role in protecting liver development under different stress conditions by serving as a secreted signaling molecule/modulator.	26901320
2012-02-18 10:35:00	Data suggest that leg1a (NP_001093526.1) and leg1b (NP_998368.1) expression are differentially regulated.	21857963

名称对应

Type	IDs
Synonymous	Leg1-B, zgc:77778
Gene	UniProtKB-ID: LEG1B_DANRE UniprotKB: Q4QRF7 UniParc: UPI0005A5D021 EMBL: BC097023, BC065450 KO: dre:406484
Nucleutide sequences	EMBL-CDS: AAH97023.1, AAH65450.1 Gene_ORFName: zgc:77778
Protein sequencees	RefSeq: NP_998368.1
Others	UniRef100: UniRef100_Q4QRF7 UniRef90: UniRef90_A5PF61 UniRef50: UniRef50_A5PF61 UniGene: Dr.162096

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
32144352	Evolutionary and Molecular Characterization of liver-enriched gene 1. Sci Rep Yanna Dang , Jin-Yang Wang , Chen Liu , Kun Zhang , Peng Jinrong , Jin He	2020-03-06	-
28252024	Evolution of complexity in the zebrafish synapse proteome. Nat Commun Ãlex BayÃ©s , Mark O Collins , Rita Reig-Viader , Gemma Gou , David Goulding , Abril Izquierdo , Jyoti S Choudhary , Richard D Emes , Seth G N Grant	2017-03-02	-
26901320	Liver-Enriched Gene 1, a Glycosylated Secretory Protein, Binds to FGFR and Mediates an Anti-stress Pathway to Protect Liver Development in Zebrafish. PLoS Genet. Minjie Hu , Yun Bai , Chunxia Zhang , Feng Liu , Zongbin Cui , Jun Chen , Jinrong Peng	2016-02-01	-
26469318	RFX transcription factors are essential for hearing in mice. Nat Commun Ran Elkon , Beatrice Milon , Laura Morrison , Manan Shah , Sarath Vijayakumar , Manoj Racherla , Carmen C Leitch , Lorna Silipino , Shadan Hadi , MichÃ¨le Weiss-Gayet , EmmanuÃ¨le Barras , Christoph D Schmid , Aouatef Ait-Lounis , Ashley Barnes , Yang Song , David J Eisenman , Efrat Eliyahu , Gregory I Frolenkov , Scott E Strome , BÃ©nÃ©dicte Durand , Norann A Zaghloul , Sherri M Jones , Walter Reith , Ronna Hertzano	2015-10-15	-
25064622	Gene expression markers in the zebrafish embryo reflect a hepatotoxic response in animal models and humans. Toxicol. Lett. Marja Driessen , Anne S Kienhuis , Alexa P Vitins , Jeroen L A Pennings , Tessa E Pronk , Evert-Jan van den Brandhof , Marianne Roodbergen , Bob van de Water , Leo T M van der Ven	2014-10-01	cyp24a1, zgc:163022, pklr, impdh1b, cyp2aa3, scg5, zgc:77778, zgc:101858, sqrdl, zgc:154142, tcap, cyp4v7, cyp2k19, cyp19a1b, aifm4, slc2a9l2
25000307	Hypoxia-inducible factor 2 alpha is essential for hepatic outgrowth and functions via the regulation of leg1 transcription in the zebrafish embryo. PLoS ONE Tzung-Yi Lin , Chi-Fu Chou , Hsin-Yu Chung , Chia-Yin Chiang , Chung-Hao Li , Jen-Leih Wu , Han-Jia Lin , Tun-Wen Pai , Chin-Hwa Hu , Wen-Shyong Tzou	2014-01-01	-
23413775	Novel blood collection method allows plasma proteome analysis from single zebrafish. J. Proteome Res. Fatemeh Babaei , Rajkumar Ramalingam , Amy Tavendale , Yimin Liang , Leo So Kin Yan , Paul Ajuh , Shuk Han Cheng , Yun Wah Lam	2013-04-05	tfa, vtg3, hpx, zgc:77778, zgc:92880, si:ch211-5k11.6, zgc:110216, amotl2a, si:dkey-61p9.7, vtg6, vtg1, vtg7, vtg2, f13a1b, plxnb2a, c5, vtg4, asb18, cp
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21857963	liver-enriched gene 1a and 1b encode novel secretory proteins essential for normal liver development in zebrafish. PLoS ONE Changqing Chang , Minjie Hu , Zhihui Zhu , Li Jan Lo , Jun Chen , Jinrong Peng	2011-01-01	-
12477932	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team	2002-12-24	-

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