| Type | Description |
|---|---|
| Definition | leukocyte receptor tyrosine kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 12:03:00 | LTK-to-Sec12 signaling represents the first example of an endoplasmic reticulum-resident signaling module with the potential to regulate proteostasis. | 31227593 |
| 2016-08-20 12:15:00 | Data show FAM150B, which was named as augmentor-alpha (AUG-alpha), binds and activtes both anaplastic lymphoma kinase (ALK) and tyrosine kinase (LTK). | 26630010 |
| 2015-04-18 11:07:00 | Only two related secreted factors, FAM150A and FAM150B (family with sequence similarity 150 member A and member B), stimulated LTK phosphorylation. | 25331893 |
| 2012-08-04 10:23:00 | aberrant activation of LTK may contribute to neoplastic cell growth. | 22347506 |
| 2010-01-21 00:00:00 | polymorphic LTKs cause up-regulation of the PI3K pathway and possibly form one genetic component of susceptibility to abnormal proliferation of self-reactive B cells in systemic lupus erythematosus | 14695357 |
| Type | IDs |
|---|---|
| Synonymous | TYK1 |
| Gene |
UniProtKB-ID:
LTK_HUMAN
UniprotKB:
P29376
UniParc:
UPI0000F53494,
UPI000013D463,
UPI0000F53493,
UPI000013D464,
UPI000181C9DB
EMBL:
AK296892,
X52213,
AC087721,
AC016134,
CH471125,
D16105,
X60702
Ensembl:
ENSG00000062524
KO:
hsa:4058
|
| Nucleutide sequences |
EMBL-CDS:
BAA03679.1,
CAA43113.1,
BAG59451.1,
CAA36460.1,
EAW92496.1
Ensembl_TRS:
ENST00000355166,
ENST00000263800,
ENST00000453182
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000263800,
ENSP00000392196,
ENSP00000347293
RefSeq:
XP_011519858.1,
XP_024305686.1,
NP_002335.2,
XP_024305687.1,
NP_996844.1,
XP_016877672.1,
XP_011519859.1,
NP_001129157.1,
XP_016877671.1,
XP_016877670.1
|
| Others |
UniRef100:
UniRef100_P29376
UniRef90:
UniRef90_P29376
UniRef50:
UniRef50_P29376
UniGene:
Hs.434481
CCDS:
CCDS10077.1,
CCDS10078.1,
CCDS45237.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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