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405763 kcnh6a

405763

kcnh6a

potassium voltage-gated channel, subfamily H (eag-related), member 6a

protein-coding

Danio rerio

基因描述

Type Description
Definition potassium voltage-gated channel, subfamily H (eag-related), member 6a

研究结论

Date Results Publications
2015-03-07 10:38:00 RNF207 is an important regulator of action potential duration, likely via effects on HERG trafficking and localization in a heat shock protein-dependent manner. 25281747
2010-07-19 11:23:00 The data support the conclusion that zerg-2 and zerg-3 are apparent orthologues of different human genes encoding potassium ion channels, but that their functions have switched compared to the respective human proteins. 20438705
2010-01-21 00:00:00 role for ERG in leukocytes, where inhibition or translational knockdown of ERG resulted in significant attenuation of the inflammatory response to an infectious stimulus 17431092
2010-01-21 00:00:00 Mutations in kcnh2 recapitulate the human long QT syndrome (LQTS) phenotype as manifested by prolongation of action potentials and prolonged QT interval in the first animal genetic model of human LQTS type 2. 17592134
2010-01-21 00:00:00 The reg mutation in the voltage sensor of the ether-a-go-go-related gene gene K+ channel causes premature zERG channel activation & defective inactivation, resulting in shortened action-potential duration & accelerated cardiac repolarization 18250272

名称对应

Type IDs
Synonymous erg, kcnh2, kcnh6
Gene
UniProtKB-ID: Q8JH78_DANRE
UniprotKB: Q8JH78
UniParc: UPI00000FCCD0
EMBL: AF532865
KO: dre:405763
Nucleutide sequences
EMBL-CDS: AAM95975.1
Protein sequencees
RefSeq: XP_005164064.1, XP_005164065.1, NP_998002.1, XP_009297800.1
Others
UniRef100: UniRef100_Q8JH78
UniRef90: UniRef90_Q8JH78
UniRef50: UniRef50_Q8JH78
UniGene: Dr.81739

全选

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研究热度

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