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40517 alpha-Cat

40517

alpha-Cat

alpha Catenin

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition alpha Catenin

研究结论

Date Results Publications
2020-06-06 13:41:00 this study shows that recruitment of Jub by alpha-catenin promotes Yki activity and Drosophila wing growth 30659113
2020-02-22 11:21:00 our findings indicate that a-Cat acts through multiple mechanisms to control tissue growth, including regulation of AJ stability, mechanosensitive Ajuba recruitment, and dynamic direct F-actin interactions. 31697683
2017-08-05 11:38:00 alpha-Catenin controls actomyosin dynamics by stabilising and promoting the formation of actomyosin foci, and also stabilises DE-Cadherin (Drosophila E-Cadherin, also known as Shotgun) at the cell membrane, suggesting that medioapical actomyosin contractility regulates junction stability. 27831494
2013-07-13 13:16:00 Increased Rap1 activity restricts epithelial invagination in an alpha-catenin-dependent manner. 23623612
2013-06-08 10:54:00 alpha-Cat mutant phenotype can be rescued by the expression of a DE-cadherin::alpha-Catenin fusion protein, which argues against an essential cytosolic, cadherin-independent role of Drosophila alpha-Catenin 22266901

名称对应

Type IDs
Synonymous CG17947, CT39986, Dalpha-Cat, Dalpha-cat, DalphaC, Dalphacat, Dmcatp, Dmel\CG17947, LD30423p, a-Cat, a-cat, alpha-CAT, alpha-cat, alpha-catenin, alpha-ctn, alphaCAT, alphaCat, alphacat
Gene
UniProtKB-ID: CTNA_DROME, X2JBG9_DROME
UniprotKB: P35220, X2JBG9
UniParc: UPI0002B8CDD0, UPI0000124700
EMBL: AE014296, D13964, AY051780
EnsemblGenome: FBgn0010215
KO: dme:Dmel_CG17947
Nucleutide sequences
EMBL-CDS: BAA03067.2, AAF45466.1, AAK93204.1, AHN58179.1
Gene_ORFName: CG17947, CG17947, Dmel_CG17947
EnsemblGenome_TRS: FBtr0070038, FBtr0339894
Protein sequencees
EnsemblGenome_PRO: FBpp0070037, FBpp0308926
RefSeq: NP_524219.1, NP_001287154.1
Others
UniRef100: UniRef100_X2JBG9, UniRef100_P35220
UniRef90: UniRef90_X2JBG9, UniRef90_P35220
UniRef50: UniRef50_X2JBG9, UniRef50_P35220
UniGene: Dm.7158

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