| Type | Description |
|---|---|
| Definition | lymphotoxin beta |
| Date | Results | Publications |
|---|---|---|
| 2018-06-23 10:34:00 | Combination of an EGFR tyrosine kinase inhibitor and a NF-kappaB inhibitor effectively suppressed cetuximab-resistant HNSCC and interfering with the EGFR-LTbeta interaction reverses resistance. | 28196873 |
| 2013-02-23 10:04:00 | TNF is able to upregulate LT-beta expression in hepatic cells at the transcriptional level by the binding of NF-kappaB p50/p65 heterodimers and Ets1 to their respective sites in the LT-beta promoter. | 22742857 |
| 2013-01-12 11:17:00 | The multifaceted character of lymphotoxin beta may be involved in inflammatory myopathies and muscular dystrophies. | 22652080 |
| 2012-07-07 11:23:00 | A strong association was found between several single nucleotide polymorphisms in the LTA/LTB/TNFalpha locus and Sjogren syndrome. | 22294627 |
| 2011-07-23 11:16:00 | Data show differential expression of interferon-gamma, TNFSF3, TNFSF10, TNFSF12 and PDGFbeta in CD8+, CD14+ and CD4+ cells. | 21211989 |
| Type | IDs |
|---|---|
| Synonymous | TNFC, TNFSF3, TNLG1C, p33 |
| Gene |
UniProtKB-ID:
TNFC_HUMAN,
Q5STB2_HUMAN
UniprotKB:
Q06643,
Q5STB2
UniParc:
UPI000000D743,
UPI000002B584
EMBL:
BA000025,
U79029,
AB088106,
AY070219,
L11016,
AY216497,
BC069330,
AB103612,
AB202114,
AF129756,
Y14768,
L11015,
AK312210,
KY500414,
BC093783,
U89922,
CH471081
Ensembl:
ENSG00000231314,
ENSG00000227507,
ENSG00000223448,
ENSG00000238114,
ENSG00000236925,
ENSG00000236237,
ENSG00000204487,
ENSG00000206437
KO:
hsa:4050
|
| Nucleutide sequences |
EMBL-CDS:
AAL49955.1,
CAA75069.1,
EAX03425.1,
AAH69330.1,
BAB63395.1,
AAC51769.1,
AAA99888.1,
AAL49954.1,
BAG35143.1,
AAH93783.1,
AAO21134.1,
AAA36191.1,
AAB37342.1,
AAD18089.1,
BAE78640.1,
AQY76901.1,
BAF31273.1,
EAX03426.1,
BAC54938.1
Gene_ORFName:
hCG_43683
Ensembl_TRS:
ENST00000444479,
ENST00000429299,
ENST00000421268,
ENST00000383493,
ENST00000376117,
ENST00000446745,
ENST00000456113,
ENST00000420402,
ENST00000457552
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000404014,
ENSP00000395102,
ENSP00000393693,
ENSP00000365285,
ENSP00000404450,
ENSP00000416113,
ENSP00000372985,
ENSP00000410481,
ENSP00000398741
RefSeq:
NP_002332.1,
NP_033666.1
|
| Others |
UniRef100:
UniRef100_Q06643
UniRef90:
UniRef90_Q06643
UniRef50:
UniRef50_Q06643
UniGene:
Hs.376208
CCDS:
CCDS4703.1,
CCDS4704.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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