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405 ARNT

405

ARNT

aryl hydrocarbon receptor nuclear translocator

protein-coding

Homo sapiens

基因描述

Type Description
Definition aryl hydrocarbon receptor nuclear translocator

研究结论

Date Results Publications
2020-09-26 13:08:00 [Arylhydrocarbon receptor nuclear translocator (ARNT) in human skin during aging.] 32593246
2020-03-14 12:53:00 Overexpression of the aryl hydrocarbon receptor nuclear translocator partially rescues fetoplacental angiogenesis in severe fetal growth restriction. 31189688
2019-11-16 13:34:00 ARNT/HIF-1beta might represent a novel biomarker for risk stratification and prognosis of HRMM patients, as well as a potential therapeutic target for overcoming 1q21 gain- or microenvironment-mediated and acquired drug resistance in MM. 29926531
2019-10-05 11:52:00 we showed that VRCZ metabolites plus UVA generated reactive oxygen species and resultant DNA damage of the epidermis, but did not induce substantial apoptosis in human keratinocytes (KCs). Furthermore, VRCZ per se stimulates aryl hydrocarbon receptor (AhR) and upregulates COX-2, which is a pivotal enzyme for the promotion of UV-associated tumors, in an AhR-ARNT dependent manner of the classical (genomic) pathway. 29568008
2019-09-21 11:40:00 We identified a protective mechanism controlled by the transcription factor ARNT that effectively inhibits progression of chronic kidney injury by transcriptional induction of ALK3, the principal mediator of antifibrotic and proregenerative bone morphogenetic protein-signaling (BMP-signaling) responses. 29664738

名称对应

Type IDs
Synonymous HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2
Gene
UniProtKB-ID: ARNT_HUMAN, A8K6P0_HUMAN, B0AZM1_HUMAN, Q53F30_HUMAN
UniprotKB: P27540, A8K6P0, B0AZM1, Q53F30
UniParc: UPI00005A72CD, UPI00016333DD, UPI0000030984, UPI000002A3F6, UPI0001639630, UPI000050A9CA, UPI00015DA8AB
EMBL: AK223459, AJ404852, M69238, AJ404851, AJ404853, AJ251863, AK293027, AB209877, AK313780, AL355860, AK290177, AK291705, Y18859, AK315812, CH471121, AY430083, AL834279, AJ404854
Ensembl: ENSG00000143437
KO: hsa:405
Nucleutide sequences
EMBL-CDS: EAW53513.1, EAW53510.1, AAQ96598.1, BAG36518.1, BAF82866.1, BAF85716.1, AAA51777.1, CAC21446.1, CAD38953.1, BAD93114.1, BAF84394.1, BAF98703.1, BAD97179.1
Ensembl_TRS: ENST00000358595, ENST00000505755, ENST00000515192, ENST00000354396
Protein sequencees
Ensembl_PRO: ENSP00000346372, ENSP00000423851, ENSP00000427571, ENSP00000351407
RefSeq: XP_011507848.1, NP_001659.1, XP_016856781.1, XP_011507849.1, XP_016856777.1, XP_005245208.1, XP_005245214.1, XP_016856785.1, NP_001184254.1, NP_001337153.1, NP_848514.1, XP_016856783.1, NP_001337155.1, XP_016856779.1, XP_016856782.1, NP_001272965.1, NP_001272964.1, NP_001337154.1, XP_016856778.1, XP_016856784.1, XP_011507847.1, XP_011507845.1, XP_016856780.1, XP_005245210.1
Others
UniRef100: UniRef100_B0AZM1, UniRef100_P27540, UniRef100_A8K6P0, UniRef100_Q53F30
UniRef90: UniRef90_O43392, UniRef90_P27540-3, UniRef90_P27540
UniRef50: UniRef50_O43392, UniRef50_P27540
UniGene: Hs.632446
CCDS: CCDS970.1, CCDS971.1, CCDS65641.1, CCDS65642.1

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