Type | Description |
---|---|
Definition | leukotriene A4 hydrolase |
Date | Results | Publications |
---|---|---|
2021-02-20 13:34:00 | Identification of Human Leukotriene A4 Hydrolase Inhibitors Using Structure-Based Pharmacophore Modeling and Molecular Docking. | 32580506 |
2020-06-27 12:17:00 | the identification of FSCN1-binding partners enhances understanding of the mechanism of FSCN1-mediated malignant phenotypes, and these findings indicate that FSCN1 binds to AIMP1 and LTA4H might promote the progression of laryngeal squamous cell carcinoma . | 31287215 |
2020-02-01 11:01:00 | Gliotoxin suppresses the biosynthesis of the potent neutrophil chemoattractant LTB4 by direct interference with LTA4H thereby impairing neutrophil functions in invasive aspergillosis. | 30745237 |
2020-01-11 10:13:00 | Low LTA4H expression is associated with antidiastole of tuberculous pleural effusion. | 30791695 |
2019-12-21 10:44:00 | the current study demonstrates the ability of eosinophils to express LTA4H and generate LTB4 in response to their activation. Eosinophil derived LTB4 likely contributes to the presence and severity of inflammation in asthma, in particular, those presentations characterized by prominent eosinophilia (and a paucity of neutrophils). | 30352167 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
LKHA4_HUMAN,
A0A140VK27_HUMAN
UniprotKB:
P09960,
A0A140VK27
UniParc:
UPI0001AE6B00,
UPI00020CE230,
UPI00003FE1B3,
UPI0000111C40
EMBL:
U27276,
U27286,
U27290,
U27280,
U27288,
U43410,
U27275,
U27293,
AK298017,
U27292,
U27281,
CH471054,
BX647158,
U27285,
U43411,
U27278,
U27289,
U27287,
U27283,
AC007298,
U27279,
BC032528,
U27282,
U27291,
CR457068,
HM005567,
J02959,
U27284,
J03459,
U27277
Ensembl:
ENSG00000111144
KO:
hsa:4048
|
Nucleutide sequences |
EMBL-CDS:
AAA36177.1,
AAH32528.1,
AAA36176.1,
EAW97559.1,
BAG60321.1,
CAG33349.1,
AAA89077.1,
AEE61164.1
Ensembl_TRS:
ENST00000228740,
ENST00000552789,
ENST00000413268
|
Protein sequencees |
Ensembl_PRO:
ENSP00000228740,
ENSP00000449958,
ENSP00000395051
RefSeq:
NP_001243573.1,
XP_011536651.1,
NP_001243572.1,
XP_005268928.1,
NP_000886.1
|
Others |
UniRef100:
UniRef100_P09960
UniRef90:
UniRef90_P09960
UniRef50:
UniRef50_P09960
UniGene:
Hs.524648
CCDS:
CCDS58267.1,
CCDS58266.1,
CCDS9059.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员