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40433 Nopp140

40433

Nopp140

Nopp140

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Nopp140

研究结论

Date Results Publications
2016-03-05 11:11:00 Nopp140 is not required for overall nucleolar integrity, but is required for 2'-O-methylation. Loss of Nopp140 impairs 2'-O-methylation of 18S and 28S rRNA. 25384888
2013-09-28 10:38:00 occurrence of apoptosis, autophagy and phenoloxidase A3 release to the hemolymph upon nucleolar stress correlated well with the demonstrated activation of Jun N-terminal kinase (JNK) in Nopp140-depleted larvae 23412656
2010-01-21 00:00:00 Data show that knockdown of Nopp140 induces Minute-like phenotypes in Drosophila that are reminiscent of human craniofacial malformations associated with Treacher Collins syndrome. 17392509
2010-01-21 00:00:00 Two splice variants of Nopp140 11809845
2010-01-21 00:00:00 Pole cells contained GFP-Nopp140 during the syncytial embryonic stages, but their nucleologenesis started at gastrulation. 16158326

名称对应

Type IDs
Synonymous CG7421, DmNopp140, Dmel\CG7421, Nopp- 140, nopp140
Gene
UniProtKB-ID: Q9VNX6_DROME, M9PFZ1_DROME, M9MSM4_DROME, Q7KTV5_DROME
UniprotKB: Q9VNX6, M9PFZ1, M9MSM4, Q7KTV5
UniParc: UPI00000073FC, UPI0002942994, UPI00000073FB, UPI00001E1D7D
EMBL: BT021407, AE014296
EnsemblGenome: FBgn0037137
KO: dme:Dmel_CG7421
Nucleutide sequences
EMBL-CDS: AAF51788.3, AAX33555.1, AGB94888.1, ADV37594.2, AAF51789.2
Gene_ORFName: Dmel_CG7421, CG7421, Dmel_CG7421, CG7421, CG7421, Dmel_CG7421, CG7421, Dmel_CG7421
EnsemblGenome_TRS: FBtr0089580, FBtr0332811, FBtr0332812, FBtr0089579
Protein sequencees
EnsemblGenome_PRO: FBpp0089003, FBpp0305034, FBpp0305035, FBpp0088542
RefSeq: NP_730693.1, NP_001189158.2, NP_730694.2, NP_001262195.1
Others
UniRef100: UniRef100_M9PFZ1, UniRef100_M9MSM4, UniRef100_Q9VNX6, UniRef100_Q7KTV5
UniRef90: UniRef90_M9PFZ1
UniRef50: UniRef50_M9PFZ1
UniGene: Dm.3277

全选

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