| Type | Description |
|---|---|
| Definition | LDL receptor related protein associated protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:16:00 | Rhegmatogenous Retinal Detachment in Nonsyndromic High Myopia Associated with Recessive Mutations in LRPAP1. | 31607522 |
| 2019-06-01 13:03:00 | LRPAP1 can be used for a novel therapeutic approach that targets mantle cell lymphomas with LRPAP1-reactive BCRs with high specificity | 29955130 |
| 2017-05-13 22:32:00 | data also reveal that D1D2 is able to bind to a second distinct site on LRP1 to form a monovalent complex. The studies confirm the canonical model for ligand recognition by this class of receptors, which is initiated by pairs of lysine residues that dock into acidic pockets on the receptor | 27402839 |
| 2016-06-11 12:13:00 | The clinical and biometric features we describe in this report characterize LRPAP1-related high myopia and should raise suspicion for mutations in the gene. | 26271838 |
| 2015-04-11 10:58:00 | The inhibition caused by reagents that prevented the activation of Rap was reversed by mobilizing intracellular calcium pharmacologically, whereas that caused by acrosome reaction inhibitors that impeded Rab3's binding to GTP was not. | 25159528 |
| Type | IDs |
|---|---|
| Synonymous | A2MRAP, A2RAP, HBP44, MRAP, MYP23, RAP, alpha-2-MRAP |
| Gene |
UniProtKB-ID:
AMRP_HUMAN
UniprotKB:
P30533
UniParc:
UPI00000354C2
EMBL:
CH471131,
AL590235,
AF035760,
AF035761,
AF035764,
M63959,
AF035763,
AF035762,
U06976,
BC112067,
AK222504,
AF035766,
AF035767,
AK222527,
BC105074,
AF035765
Ensembl:
ENSG00000163956
KO:
hsa:4043
|
| Nucleutide sequences |
EMBL-CDS:
AAI12068.1,
EAW82460.1,
BAD96224.1,
AAA87889.1,
BAD96247.1,
AAA51553.1,
AAC67373.1,
EAW82461.1,
AAI05075.1
Ensembl_TRS:
ENST00000650182
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000497444
RefSeq:
NP_002328.1
|
| Others |
UniRef100:
UniRef100_P30533
UniRef90:
UniRef90_P30533
UniRef50:
UniRef50_P30533
UniGene:
Hs.40966
CCDS:
CCDS3371.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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