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403955 RAC1

403955

RAC1

Rac family small GTPase 1

protein-coding

Canis lupus familiaris

基因描述

Type Description
Definition Rac family small GTPase 1

研究结论

Date Results Publications
2018-12-14 16:23:00 Live cell imaging with cell cycle indicators showed that expression of Rac1V12, but not the wild-type Rac1 or Rac1b, promoted cell cycle progression. The expression of Rac1b per se cannot induce cell proliferation. 23411476
2017-12-09 10:26:00 Silencing tight junction protein ZO-2 alters epithelial cytoarchitecture.ZO-2 silencing increases RhoA activity through GEF-H1 recruitment to cell borders.ZO-2 silencing activates Cdc42 and triggers mitotic spindle disorientation. ZO-2 silencing increases Rac1 and cofilin activity and lamellipodia formation. 28554775
2017-12-02 10:39:00 Data indicate exosomal Rac1/PAK2 as angiogenic promoters. 26919098
2013-05-25 10:31:00 This inversion of glandular orientation is accompanied by Rac1 inactivation during early cystogenesis, and temporal activation of Rac1 is sufficient to recover the normal cyst phenotype. 23051733
2011-07-09 12:09:00 These results indicate that cadherins and nectins cooperate to induce and then rapidly suppress Rac1 activity during initial cell-cell adhesion. 21412440

名称对应

Type IDs
Synonymous RAC2
Gene
UniProtKB-ID: RAC1_CANLF
UniprotKB: P62999
UniParc: UPI000000060F
EMBL: X56390
Ensembl: ENSCAFG00040013856, ENSCAFG00030017683
KO: cfa:403955
Nucleutide sequences
EMBL-CDS: CAA39801.1
Ensembl_TRS: ENSCAFT00030032776, ENSCAFT00040025732
Protein sequencees
Ensembl_PRO: ENSCAFP00040022379, ENSCAFP00030028596
RefSeq: XP_005621078.1, XP_022275186.1, NP_001003274.1
Others
UniRef100: UniRef100_P63000
UniRef90: UniRef90_P63000
UniRef50: UniRef50_P63000
UniGene: Cfa.40290

全选

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研究热度

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