| Type | Description |
|---|---|
| Definition | ras homolog family member A |
| Date | Results | Publications |
|---|---|---|
| 2017-12-09 10:26:00 | Silencing tight junction protein ZO-2 alters epithelial cytoarchitecture.ZO-2 silencing increases RhoA activity through GEF-H1 recruitment to cell borders.ZO-2 silencing activates Cdc42 and triggers mitotic spindle disorientation. ZO-2 silencing increases Rac1 and cofilin activity and lamellipodia formation. | 28554775 |
| 2014-05-03 11:20:00 | RhoA controls the development cell migration fingers through mechanical cues. | 24561621 |
| 2013-01-05 10:55:00 | the RhoA-mediated assembly of adhesome complexes is a fundamental step in the signal transduction process in response to agonist -induced smooth muscle contraction. | 22893699 |
| 2011-05-21 10:10:00 | the TNF-alpha-induced activation of the ERK/GEF-H1/RhoA pathway in tubular cells is mediated through Src- and TACE-dependent EGFR activation. | 21212278 |
| 2010-08-23 11:58:00 | Activation of the small GTPase RhoA plays a critical role in the regulation of force generation in intact airway smooth muscle tissues activated by muscarinic stimulation. | 20445174 |
| Type | IDs |
|---|---|
| Synonymous | RHO1 |
| Gene |
UniProtKB-ID:
F6XY66_CANLF
UniprotKB:
F6XY66
UniParc:
UPI0000046824
EMBL:
AAEX03012230,
AAEX03012231
Ensembl:
ENSCAFG00000023066
KO:
cfa:403954
|
| Nucleutide sequences |
Ensembl_TRS:
ENSCAFT00000035203
|
| Protein sequencees |
Ensembl_PRO:
ENSCAFP00000030438
RefSeq:
NP_001003273.2,
XP_005632367.1
|
| Others |
UniRef100:
UniRef100_P61586
UniRef90:
UniRef90_P61586
UniRef50:
UniRef50_P61586
UniGene:
Cfa.20231
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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