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403954 RHOA

403954

RHOA

ras homolog family member A

protein-coding

Canis lupus familiaris

基因描述

Type Description
Definition ras homolog family member A

研究结论

Date Results Publications
2017-12-09 10:26:00 Silencing tight junction protein ZO-2 alters epithelial cytoarchitecture.ZO-2 silencing increases RhoA activity through GEF-H1 recruitment to cell borders.ZO-2 silencing activates Cdc42 and triggers mitotic spindle disorientation. ZO-2 silencing increases Rac1 and cofilin activity and lamellipodia formation. 28554775
2014-05-03 11:20:00 RhoA controls the development cell migration fingers through mechanical cues. 24561621
2013-01-05 10:55:00 the RhoA-mediated assembly of adhesome complexes is a fundamental step in the signal transduction process in response to agonist -induced smooth muscle contraction. 22893699
2011-05-21 10:10:00 the TNF-alpha-induced activation of the ERK/GEF-H1/RhoA pathway in tubular cells is mediated through Src- and TACE-dependent EGFR activation. 21212278
2010-08-23 11:58:00 Activation of the small GTPase RhoA plays a critical role in the regulation of force generation in intact airway smooth muscle tissues activated by muscarinic stimulation. 20445174

名称对应

Type IDs
Synonymous RHO1
Gene
UniProtKB-ID: F6XY66_CANLF
UniprotKB: F6XY66
UniParc: UPI0000046824
EMBL: AAEX03012230, AAEX03012231
Ensembl: ENSCAFG00000023066
KO: cfa:403954
Nucleutide sequences
Ensembl_TRS: ENSCAFT00000035203
Protein sequencees
Ensembl_PRO: ENSCAFP00000030438
RefSeq: NP_001003273.2, XP_005632367.1
Others
UniRef100: UniRef100_P61586
UniRef90: UniRef90_P61586
UniRef50: UniRef50_P61586
UniGene: Cfa.20231

全选

研究热度
该基因近6年没有文献发表
热点单位
排名 科研单位 文献
1

Indiana University School of Medicine

2
2

University of Geneva

2
3

Stanford University

1
4

European Molecular Biology Laboratory, Heidelberg, Federal Republic of Germany.

1
5

Keenan Research Centre in the Li Ka Shing Knowledge Institute

1
热点人员
排名 研究人员 文献
1

Susan J Gunst

2
2

Wenwu Zhang

2
3

Sandra Citi

2
4

B Ladoux

1
5

M Reffay

1
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