KRAS - KRAS proto-oncogene, GTPase-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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403871 KRAS

基因描述

Type	Description
Definition	KRAS proto-oncogene, GTPase

研究结论

Date	Results	Publications
2017-10-28 10:45:00	These results delineate the signaling cascades connecting oncogenic K-Ras(V12) with alpha6- and alphaV-integrin functions to modulate cancer cell survival and tumorigenesis, and reveal new possible strategies to target highly oncogenic K-Ras(V12) mutants.	28604746
2017-04-15 12:03:00	KRAS mutations do not play a critical role in feline or canine pancreatic acinar cell carcinomas	27290644
2014-07-19 12:34:00	Study shows that the recycling endosome collects solubilized KRas from endomembranes to redirect it back to the plasma membrane.	24725411
2013-07-20 11:21:00	KRAP mediates InsP(3)R clustering in confluent MDCK cells and functions as an adapter, linking InsP(3)Rs to vimentin intermediate filaments.	22946050
2012-12-08 10:59:00	Activated Ras protein accelerates cell cycle progression to perturb Madin-Darby canine kidney cystogenesis	22829590

名称对应

Type	IDs
Synonymous	K-RAS
Gene
Nucleutide sequences
Protein sequencees	RefSeq: XP_003433609.1, XP_013963974.1
Others	UniGene: Cfa.3678

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
28604746	Oncogenic K-Ras upregulates ITGA6 expression via FOSL1 to induce anoikis resistance and synergizes with Î±V-Class integrins to promote EMT. Oncogene K Zhang , S-M MyllymÃ¤ki , P Gao , R Devarajan , V KytÃ¶lÃ¤ , M Nykter , G-H Wei , A Manninen	2017-10-12	-
27290644	KRAS Mutations in Canine and Feline Pancreatic Acinar Cell Carcinoma. J. Comp. Pathol. C Crozier , G A Wood , R A Foster , S Stasi , J H W Liu , J M S Bartlett , B L Coomber , V S Sabine	2016-07-01	-
24725411	KRas localizes to the plasma membrane by spatial cycles of solubilization, trapping and vesicular transport. Cell Malte Schmick , Nachiket Vartak , BjÃ¶rn Papke , Marija Kovacevic , Dina C Truxius , Lisaweta Rossmannek , Philippe I H Bastiaens	2014-04-10	-
22946050	Vimentin and the K-Ras-induced actin-binding protein control inositol-(1,4,5)-trisphosphate receptor redistribution during MDCK cell differentiation. J. Cell. Sci. Florent Dingli , Jan B Parys , Damarys Loew , Simon Saule , Laurence Mery	2012-11-15	KRAS, VIM
22829590	Activated Ras protein accelerates cell cycle progression to perturb Madin-Darby canine kidney cystogenesis. J Biol Chem Atsuro Sakurai , Michiyuki Matsuda , Etsuko Kiyokawa	2012-09-14	-
9501305	High sequence similarity within ras exons 1 and 2 in different mammalian species and phylogenetic divergence of the ras gene family. Mamm. Genome F Watzinger , B Mayr , E Haring , T Lion	1998-03-01	-
1324792	K-ras activation in non-small cell lung cancer in the dog. Cancer Res. S A Kraegel , P H Gumerlock , D L Dungworth , V I Oreffo , B R Madewell	1992-09-01	KRAS

研究热度

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