| Type | Description |
|---|---|
| Definition | tight junction protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-09 10:26:00 | Silencing tight junction protein ZO-2 alters epithelial cytoarchitecture.ZO-2 silencing increases RhoA activity through GEF-H1 recruitment to cell borders.ZO-2 silencing activates Cdc42 and triggers mitotic spindle disorientation. ZO-2 silencing increases Rac1 and cofilin activity and lamellipodia formation. | 28554775 |
| 2017-09-02 11:21:00 | SUMOylation affects the intracellular localization of ZO-2 and its regulatory role on GSK3beta and beta-catenin signaling activity. | 27604867 |
| 2014-04-05 11:31:00 | novel posttranslational modifications of ZO-2 regulate the intracellular fate of this protein. | 23804652 |
| 2012-11-24 10:16:00 | ZO-1 and ZO-2 proteins are required not only for TJ assembly but also for regulating the organization and functional activity of the apical cytoskeleton, particularly the perijunctional actomyosin ring; these activities are relevant both to cellular organization and epithelial morphogenesis. | 22190737 |
| 2010-11-13 11:08:00 | The identification of ZASP helps to unfold the complex nuclear molecular arrays that form on ZO-2 scaffolds. | 20868680 |
| Type | IDs |
|---|---|
| Synonymous | ZO-2 |
| Gene |
UniProtKB-ID:
ZO2_CANLF,
J9P749_CANLF,
F1PEE3_CANLF,
A0A5F4D4J3_CANLF
UniprotKB:
Q95168,
J9P749,
F1PEE3,
A0A5F4D4J3
UniParc:
UPI0003AE31C2,
UPI000013C44B,
UPI000274A20D,
UPI0003AE0BAD
EMBL:
AAEX03000576,
L27152,
AAEX03000577
Ensembl:
ENSCAFG00000001902
KO:
cfa:403854
|
| Nucleutide sequences |
EMBL-CDS:
AAC37332.1
Ensembl_TRS:
ENSCAFT00000048763,
ENSCAFT00000003012,
ENSCAFT00000059505
|
| Protein sequencees |
Ensembl_PRO:
ENSCAFP00000041484,
ENSCAFP00000002794,
ENSCAFP00000060677
RefSeq:
XP_013969459.1,
XP_005615782.1,
XP_005615778.1,
XP_005615781.1,
XP_022271655.1,
XP_022271904.1,
XP_022270935.1,
XP_005615779.1,
NP_001003204.1,
XP_022270651.1
|
| Others |
UniRef100:
UniRef100_F1PEE3,
UniRef100_A0A5F4D4J3,
UniRef100_J9P749,
UniRef100_Q95168
UniRef90:
UniRef90_Q95168
UniRef50:
UniRef50_Q9UDY2
UniGene:
Cfa.1898
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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