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40385 Cdk12

40385

Cdk12

Cyclin-dependent kinase 12

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Cyclin-dependent kinase 12

研究结论

Date Results Publications
2016-12-31 11:18:00 Cdk12 suppresses genes that support metabolic functions in stressed conditions. Cdk12 is not a generally essential Pol II kinase and is not required for the transcription of essential and housekeeping genes at least in adult tissues. 26911346
2016-03-05 11:06:00 CDK12 plays a role in controlling the epigenetic transition between euchromatin and heterochromatin, suggesting a chromatin regulatory mechanism in neuronal behaviors. 26508632
2012-06-09 10:54:00 The phosphorylation of the C-terminal domain of the RNA polymerase II by Cdk12 provides an elegant mechanism in regulating timed splicing of newly synthesized mRNA molecules. 22461565

名称对应

Type IDs
Synonymous AC017581, CDK12, CG7597, Dmel\CG7597, anon-WO0140519.165, cg7597, dCDK12, gi24668141
Gene
UniProtKB-ID: CDK12_DROME, M9PG50_DROME
UniprotKB: Q9VP22, M9PG50
UniParc: UPI000007A572
EMBL: AY060835, AY069806, AE014296, BT058001
EnsemblGenome: FBgn0037093
KO: dme:Dmel_CG7597
Nucleutide sequences
EMBL-CDS: AAN12171.1, ACM16711.1, AAF51738.1, AAL39951.1, AAL28383.1, AGB94860.1
Gene_ORFName: CG7597, Dmel_CG7597, CG7597
EnsemblGenome_TRS: FBtr0332716, FBtr0078358, FBtr0078357, FBtr0078358, FBtr0078357, FBtr0332716
Protein sequencees
EnsemblGenome_PRO: FBpp0304962, FBpp0078014, FBpp0078013, FBpp0078014, FBpp0304962, FBpp0078013
RefSeq: NP_730643.1, NP_001262167.1, NP_649325.2
Others
UniRef100: UniRef100_Q9VP22
UniRef90: UniRef90_Q9VP22
UniRef50: UniRef50_Q9VP22
UniGene: Dm.1943

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