| Type | Description |
|---|---|
| Definition | LDL receptor related protein 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:13:00 | A Role of Low-Density Lipoprotein Receptor-Related Protein 4 (LRP4) in Astrocytic Abeta Clearance. | 32457076 |
| 2020-02-08 12:23:00 | Cenani-Lenz (C-L) syndrome-like phenotypes as well as other syndactyly disorders with or without metacarpal synostosis/phalangeal disorganization are also known to be associated with specific LRP4 mutations, adenomatous polyposis coli (APC) truncating mutations, genomic rearrangements of the GREM1-FMN1 locus, as well as FMN1 mutations. | 30569497 |
| 2019-06-01 11:45:00 | These results suggest that variants in the fourth beta-propeller of the extracellular protein domain may cause a phenotype distinct from previously characterized LRP4 variants. | 29524275 |
| 2019-01-26 11:46:00 | The results showed that LRP4 suppressed both Wnt/beta-Catenin and Notch signaling pathways, and these activities were perturbed either by LRP4 missense mutations or by a knockdown of LRP4. | 30327840 |
| 2018-12-22 10:03:00 | In vitro experiments demonstrated that LRP4 downregulation significantly inhibited the colony formation, proliferation, migration, and invasion of the three papillary thyroid cancer cell lines. | 29885843 |
| Type | IDs |
|---|---|
| Synonymous | CLSS, CMS17, LRP-4, LRP10, MEGF7, SOST2 |
| Gene |
UniProtKB-ID:
LRP4_HUMAN
UniprotKB:
O75096
UniParc:
UPI0000D625E9
EMBL:
AB011540,
BC037360,
BC041048,
BC136668,
AB231861,
BC136667,
AC021573,
AB084910
Ensembl:
ENSG00000134569
KO:
hsa:4038
|
| Nucleutide sequences |
EMBL-CDS:
AAH37360.1,
AAI36668.1,
BAD83615.1,
AAH41048.1,
BAE19679.1,
AAI36669.1,
BAA32468.1
Ensembl_TRS:
ENST00000378623
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000367888
RefSeq:
NP_002325.2,
XP_016873223.1,
XP_011518406.1,
XP_011518405.1
|
| Others |
UniRef100:
UniRef100_O75096
UniRef90:
UniRef90_Q8VI56
UniRef50:
UniRef50_Q8VI56
UniGene:
Hs.4930
CCDS:
CCDS31478.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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