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403649 CLDN2

403649

CLDN2

claudin 2

protein-coding

Canis lupus familiaris

基因描述

Type Description
Definition claudin 2

研究结论

Date Results Publications
2021-01-09 13:25:00 Claudin-15 forms a water channel through the tight junction with distinct function compared to claudin-2. 31188544
2017-05-27 10:48:00 hypotonic stress induces dephosphorylation, clathrin-dependent endocytosis, and degradation of claudin-1 and -2 in lysosomes, resulting in disruption of the TJ barrier in renal tubular epithelial cells. 27733684
2016-03-19 11:54:00 Claudin-2 independently determines the 'leaky' property of in MDCK II cells. 25781928
2016-02-06 11:35:00 binds to Rab14 and that duanyu1531iota requires Rab14 for its correct distribution in cells. As with Rab14, duanyu1531iota protects claudin-2 from lysosomal degradation and, in consequence, modulates epithelial barrier. 25694446
2015-12-26 10:56:00 IQGAP1 modulates TJ formation by a twofold mechanism: (1) controlling the expression and recruitment of claudin 2 and recruitment of claudin 4 to the TJ, and (2) transient inhibition of the CDC42-JNK pathway. 25588839

名称对应

Type IDs
Gene
UniProtKB-ID: CLD2_CANLF
UniprotKB: Q95KM6
UniParc: UPI0000127AAD
EMBL: AF358907
Ensembl: ENSCAFG00030022406
KO: cfa:403649
Nucleutide sequences
EMBL-CDS: AAK51433.1
Ensembl_TRS: ENSCAFT00030041176
Protein sequencees
Ensembl_PRO: ENSCAFP00030035927
RefSeq: XP_013966788.1, NP_001003089.1, XP_022271196.1, XP_022271197.1
Others
UniRef100: UniRef100_Q95KM6
UniRef90: UniRef90_P57739
UniRef50: UniRef50_P57739
UniGene: Cfa.3514

全选

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研究热度

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