| Type | Description |
|---|---|
| Definition | ryanodine receptor 2 |
| Date | Results | Publications |
|---|---|---|
| 2015-12-26 10:40:00 | The cytoplasmic interaction between junctin and RyR is required for luminal binding to replicate the influence of full junctin on RyR1 and RyR2 activity. | 25609705 |
| 2012-07-21 11:04:00 | MicroRNA-1 and -133 increase arrhythmogenesis in heart failure by dissociating phosphatase activity from RyR2 complex | 22163007 |
| 2011-01-01 10:54:00 | The defective inter-domain interaction between N-terminal and central domains within RyR2 reduces the binding affinity of CaM to RyR2, thereby causing the spontaneous Ca(2+) release events in failing hearts. | 20388639 |
| 2010-03-01 11:19:00 | Redox modulation of RyRs promotes generation of Ca(2+) alternans by enhancing the steepness of the Ca(2+) release-load relationship and thereby providing a substrate for post-myocardial infarction arrhythmias. | 19617226 |
| 2010-02-08 11:48:00 | Under conditions of continuous activation by cytosolic Ca(2+), RyR2s can periodically cycle between open and deactivated states due to effects of luminal Ca(2+). | 19703963 |
| Type | IDs |
|---|---|
| Gene | |
| Nucleutide sequences | |
| Protein sequencees |
RefSeq:
XP_022273677.1
|
| Others |
UniGene:
Cfa.2408
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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