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403548 ALPL

403548

ALPL

alkaline phosphatase, biomineralization associated

protein-coding

Canis lupus familiaris

基因描述

Type Description
Definition alkaline phosphatase, biomineralization associated

研究结论

Date Results Publications
2020-08-15 19:06:00 A homozygous missense variant in the alkaline phosphatase gene ALPL is associated with a severe form of canine hypophosphatasia. 30700765
2016-09-03 10:06:00 This study showed that canine osteosarcoma cells express endothelin-1 and functional endothelin A receptors; increases in bone alkaline phosphatase activity are associated with osteoblastic OS lesions. 26426813
2014-02-22 12:26:00 It was concluded that tumor burden is a determinant of serum alkaline phosphatase activity in dogs with appendicular osteosarcoma. 23734720
2012-12-08 11:04:00 The results of this study suggest that there are sex differences in biochemical markers of bone turnover in dogs which should be considered in interpretation of bone marker data. 22296940
2012-02-18 11:07:00 No significant difference in beta-catenin expression or activation between osteosarcoma populations differing in serum ALP concentration. 22022527

名称对应

Type IDs
Synonymous ALP
Gene
UniProtKB-ID: F1PF95_CANLF
UniprotKB: F1PF95
UniParc: UPI000274922C
EMBL: AAEX03001783, AAEX03001784
Ensembl: ENSCAFG00000014853
Nucleutide sequences
Ensembl_TRS: ENSCAFT00000023578
Protein sequencees
Ensembl_PRO: ENSCAFP00000021891
RefSeq: XP_005617269.1, NP_001184066.1, XP_005617271.1, XP_005617270.1
Others
UniRef100: UniRef100_A0A5F4DGF5
UniRef90: UniRef90_A0A3Q2LA46
UniRef50: UniRef50_P05186-2
UniGene: Cfa.65

全选

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研究热度

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