| Type | Description |
|---|---|
| Definition | toll like receptor 4 |
| Date | Results | Publications |
|---|---|---|
| 2019-04-27 11:04:00 | These findings indicate that TLR4 and NOD2 are remarkably associated with the severity of chronic gastrointestinal disease in dogs. | 30947975 |
| 2015-05-16 10:32:00 | These findings do not support a role for non-synonymous SNPs in the TLR 2, 4 and 9 coding regions in the pathogenesis of canine SNA, but do not exclude a role for innate immunity in the pathogenesis of the disease. | 25266752 |
| 2015-01-31 12:41:00 | Study investigated the pattern of TLR-2, TLR-4 and TLR-9 gene expression in brain, choroid plexus, spleen and lymph node of dogs naturally infected with Leishmania infantum. In the brain, there was only an upregulation of TLR-2, in the choroid plexus, TLR-2 and TLR-9 were both upregulated and peripheral lymphoid organs showed increased TLR-2 and TLR-4 expression. | 25283216 |
| 2012-01-28 11:36:00 | TLR4 is expressed in the surface epithelium, glandular epithelium and stroma throughout the estrous cycle and in pyometra. | 21752456 |
| 2011-07-09 12:18:00 | TLR4 and TLR5 polymorphisms are significantly associated with inflammatory bowel disease in German shepherd dogs | 21203467 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
Q8SQH3_CANLF,
F1PDB9_CANLF
UniprotKB:
Q8SQH3,
F1PDB9
UniParc:
UPI0000086C15,
UPI0001E5E5D1
EMBL:
AB080363,
AAEX03008139
Ensembl:
ENSCAFG00000003518
KO:
cfa:403417
|
| Nucleutide sequences |
EMBL-CDS:
BAB85609.1
Ensembl_TRS:
ENSCAFT00000005653
|
| Protein sequencees |
Ensembl_PRO:
ENSCAFP00000031395
RefSeq:
NP_001002950.2
|
| Others |
UniRef100:
UniRef100_Q8SQH3,
UniRef100_F1PDB9
UniRef90:
UniRef90_Q8SQH3,
UniRef90_F1PDB9
UniRef50:
UniRef50_O00206,
UniRef50_S5PIY9
UniGene:
Cfa.118
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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