| Type | Description |
|---|---|
| Definition | cytochrome P450 3A29 |
| Date | Results | Publications |
|---|---|---|
| 2018-10-06 10:24:00 | Data suggest high similarity in mechanisms involved in regulation of expression of pig CYP3A29 and human CYP3A4 in hepatocytes. Expression of pregnane X receptor (PXR) is correlated with expression of CYP3A29 in pig hepatocytes. | 30153482 |
| 2017-11-11 12:17:00 | Pig CYP3A29 bioactivates aflatoxin B1 in regioselective manner. | 27626447 |
| 2016-04-23 10:10:00 | The regulatory effect of IFN-gamma on CYP3A29 expression is mediated via PXR. | 25413352 |
| 2014-06-07 10:06:00 | Pregnane X receptor is required for interferon-alpha-mediated CYP3A29 expression, and its expression before CYP3A29. | 24525126 |
| 2012-03-10 10:27:00 | A correlation between individual pig CYP3A mRNA expression and in vivo hepatic extraction ratio was established which indicates that CYP3A is the major determinant factor of verapamil metabolism in both pigs and humans. | 21447389 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CP3AT_PIG
UniprotKB:
P79401
UniParc:
UPI00001281D4
EMBL:
Z93099
KO:
ssc:403324
|
| Nucleutide sequences |
EMBL-CDS:
CAB07513.1
|
| Protein sequencees |
RefSeq:
NP_999588.1
|
| Others |
UniRef100:
UniRef100_P79401
UniRef90:
UniRef90_P79401
UniRef50:
UniRef50_P79401
UniGene:
Ssc.204
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
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Ensembl: {{protein.proteinEnsembl}} |
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Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30153482 |
Comp. Biochem. Physiol. C Toxicol. Pharmacol. Yucheng He , Xiaoqiao Zhou , Xiaowen Li , Xiue Jin , Xiliang Wang , Xiaoping Pan , Dingren Bi |
2018-12-01 | - |
| 27626447 |
Bioactivation and Regioselectivity of Pig Cytochrome P450 3A29 towards Aflatoxin Bâ. Toxins (Basel) Jun Wu , Ruohong Chen , Caihui Zhang , Kangbai Li , Weiying Xu , Lijuan Wang , Qingmei Chen , Peiqiang Mu , Jun Jiang , Jikai Wen , Yiqun Deng |
2016-09-12 | - |
| 25413352 |
IFN-γ regulates cytochrome 3A29 through pregnane X receptor in pigs. Xenobiotica Xiaowen Li , Xiuzhong Hu , Xiue Jin , Xiaoqiao Zhou , Xiliang Wang , Deshi Shi , Dingren Bi |
2015-05-01 |
IFNG,
NR1I2,
CYP3A29
|
| 24525126 |
Pregnane X receptor is required for IFN-α-mediated CYP3A29 expression in pigs. Biochem. Biophys. Res. Commun. Xiaowen Li , Xiue Jin , Xiaoqiao Zhou , Xiliang Wang , Deshi Shi , Yuncai Xiao , Dingren Bi |
2014-03-07 |
NR1I2,
IFNA1,
CYP3A29
|
| 21447389 |
Drug metabolism of CYP3A4, CYP2C9 and CYP2D6 substrates in pigs and humans. Eur J Pharm Sci Helena Anna Thörn , Anna Lundahl , Johannes Antonius Schrickx , Paul Alfred Dickinson , Hans Lennernäs |
2011-06-14 | - |
| 20863320 |
Comparison of the substrate kinetics of pig CYP3A29 with pig liver microsomes and human CYP3A4. Biosci. Rep. Min Yao , Menghong Dai , Zhaoying Liu , Lingli Huang , Dongmei Chen , Yulian Wang , Dapeng Peng , Xu Wang , Zhenli Liu , Zonghui Yuan |
2011-06-01 | - |
| 17548327 |
Yi Chuan Jia-Da Yang , Hai-Tao Shang , Hong Wei , Wan-Shen Yang , Xin Liu |
2007-05-01 | - |
| 15679890 |
Comparative analysis of protein coding sequences from human, mouse and the domesticated pig. BMC Biol. Frank Grønlund Jørgensen , Asger Hobolth , Henrik Hornshøj , Christian Bendixen , Merete Fredholm , Mikkel Heide Schierup |
2005-01-01 |
NREP,
P4HA1,
LOC100037988,
RPL14,
RPL27,
RPS26,
SNRPE,
EIF4E2,
ACOX1,
COPS5,
COPS2,
COPS4,
CD302,
CNPY3,
GATM,
SUMO1,
LMO4,
HNRNPAB,
SMNDC1,
CAPZB,
PRELID3B,
AIMP1,
SPCS1,
DEGS1,
H2AFZ,
RPL7L1,
PON2,
HEXA,
UCHL5,
RAB34,
RAB5A,
RNF5,
PHGDH,
ITLN2,
TMCO1,
TAF11,
RAB2A,
VIMP,
SDCBP,
ARV1,
PMP2,
MRPL2,
TPD52,
AIG1,
C1H15orf61,
LOC100152047,
ENPP6,
COMMD4,
POLR3GL,
PLEKHO1,
SSB,
CMSS1,
AGA,
CUTA,
PEX7,
COX6A1,
PMVK,
MTERF3,
CD53,
FRZB,
PEA15,
ERH,
TMEM242,
CTHRC1,
MED6,
FAM162B,
FAM204A,
PDZK1,
DPCD,
HAUS1,
COQ10B,
BNIP3L,
SSR1,
MRPS28,
SDC2,
DHRS7,
TOMM20,
DNAJB11,
BZW1,
CXHXorf56,
GNPNAT1,
BOLA1,
PDCD7,
PFDN6,
LOC100153062,
DTWD1,
UBE2C,
STK16,
DNPEP,
ARPC2,
SIT1,
STX7,
WDR61,
PPP6C,
TIPIN,
MYF5,
MRPL13,
CHCHD1,
EAPP
|
| 14681463 |
Nucleic Acids Res. Hirohide Uenishi , Tomoko Eguchi , Kohei Suzuki , Tetsuya Sawazaki , Daisuke Toki , Hiroki Shinkai , Naohiko Okumura , Noriyuki Hamasima , Takashi Awata |
2004-01-01 |
PIK3R6,
DESI2,
ENPP1,
SPARCL1,
NREP,
SLA-3,
IRF7,
DYNC1H1,
SLA-1,
P4HA1,
DNMT3A,
SEPHS2,
SGMS1,
CPE,
BIN1,
TNFRSF1B,
SLA-DQB1,
CD14,
APOBEC3F,
PDE4B,
KCND3,
KCNIP2,
UIMC1,
LOC100037950,
C9,
C6,
C8A,
C8B,
C8G,
LOC100037957,
CAPZA2,
CTSB,
SEPP1,
LOC100037968,
SLC7A7,
C2H19orf70,
ATP5J2,
PET100,
TOMM7,
NDUFC1,
SLIRP,
LOC100037988,
COX6C,
COX7C,
NDUFV2,
PSMB7,
RPL10A,
RPL14,
RPL27,
RPS21,
RPS26,
TMSB10,
TPM1,
ATPIF1,
KLF7,
RCHY1,
PCD1B,
CD1E,
SEP15,
CCL11,
CD72,
PVRL2,
COX6B,
RPS6,
CLEC7A,
RPL4,
EIF4E,
LGALS3,
SNRPE,
ZFAND5,
ADSS,
SDHD,
C5AR1,
BTG3,
GNA14,
NAGS,
TNMD,
ABCG8,
YWHAQ,
PGRMC2,
CYB561,
CNN3,
GNAS,
RBM39,
BRCA1,
EDN3,
KRT2,
HPS4,
BLOC1S5,
BLOC1S6,
RABGGTA,
MLPH,
ATP7B,
CRYZL1,
PNPLA3,
SRGN,
SPTAN1,
BIRC6,
HPS5
|
| 9682441 |
Mapping of porcine genes belonging to two different cytochrome P450 subfamilies. Anim. Genet. P H Nissen , A K Winterø , M Fredholm |
1998-02-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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