bace1 - beta-secretase 1-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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403005 bace1

基因描述

Type	Description
Definition	beta-secretase 1

研究结论

Date	Results	Publications
2014-01-11 11:06:00	bace1 mutants display hypomyelination in the peripheral nervous system and supernumerary neuromasts while in bace2 mutants the shape and migration of melanocytes is affected.	23406323

名称对应

Type	IDs
Synonymous	zgc:77409
Gene	UniProtKB-ID: Q6NZT7_DANRE UniprotKB: Q6NZT7 UniParc: UPI000023B731 EMBL: BC065973 KO: dre:403005
Nucleutide sequences	EMBL-CDS: AAH65973.1
Protein sequencees	RefSeq: NP_991267.1
Others	UniRef100: UniRef100_Q6NZT7 UniRef90: UniRef90_Q6NZT7 UniRef50: UniRef50_Q1KLR6 UniGene: Dr.133674

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
31745184	High-fat diet impairs cognitive function of zebrafish. Sci Rep Shinichi Meguro , Sayaka Hosoi , Takahiro Hasumura	2019-11-19	-
26776728	Embryonic exposure to 10 Î¼g L(-1) lead results in female-specific expression changes in genes associated with nervous system development and function and Alzheimer's disease in aged adult zebrafish brain. Metallomics Jinyoung Lee , Jennifer L Freeman	2016-06-01	-
27189481	Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. BMC Genomics Jeremy Pasquier , CÃ©dric Cabau , Thaovi Nguyen , Elodie Jouanno , Dany Severac , Ingo Braasch , Laurent Journot , Pierre Pontarotti , Christophe Klopp , John H Postlethwait , Yann Guiguen , Julien Bobe	2016-05-18	-
23406323	Loss of Bace2 in zebrafish affects melanocyte migration and is distinct from Bace1 knock out phenotypes. J. Neurochem. Frauke van Bebber , Alexander Hruscha , Michael Willem , Bettina Schmid , Christian Haass	2013-11-01	wu:fi26d02, bace1, zgc:103530, nrg1
23527866	Fishing for function--distinct roles of Bace1 and Bace2 in Zebrafish development. J. Neurochem. Jochen Walter	2013-11-01	bace1, nrg1
23637177	Dual cleavage of neuregulin 1 type III by BACE1 and ADAM17 liberates its EGF-like domain and allows paracrine signaling. J. Neurosci. Daniel Fleck , Frauke van Bebber , Alessio Colombo , Chiara Galante , Benjamin M Schwenk , Linnea Rabe , Heike Hampel , Bozidar Novak , Elisabeth Kremmer , Sabina Tahirovic , Dieter Edbauer , Stefan F Lichtenthaler , Bettina Schmid , Michael Willem , Christian Haass	2013-05-01	-
22045484	The BACE1-PSEN-AÎ²PP regulatory axis has an ancient role in response to low oxygen/oxidative stress. J. Alzheimers Dis. Seyyed Hani Moussavi Nik , Lachlan Wilson , Morgan Newman , Kevin Croft , Trevor A Mori , Ian Musgrave , Michael Lardelli	2012-01-01	pcsk7, appb, cat, psen1, bace1, psen2, appa, tagln, BACE1, APP, PSEN1, PSEN2
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
16757811	Functional domains of the BACE1 and BACE2 promoters and mechanisms of transcriptional suppression of the BACE2 promoter in normal neuronal cells. J. Mol. Neurosci. Debomoy K Lahiri , Bryan Maloney , Yuan-Wen Ge	2006-01-01	-
12477932	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team	2002-12-24	-

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