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402998 plxnd1

402998

plxnd1

plexin D1

protein-coding

Danio rerio

基因描述

Type Description
Definition plexin D1

研究结论

Date Results Publications
2020-02-22 10:48:00 These findings expand the vascular roles of GIPCs beyond those of the (VEGF)-dependent, proangiogenic GIPC1-Neuropilin 1 complex, recasting GIPCs as negative modulators of antiangiogenic PLXND1 signaling and suggest that PLXND1 trafficking shapes vascular development. 31050647
2017-06-03 12:15:00 Sema3d regulates collective endothelial cell migration in zebrafish through two separate mechanisms. Mesenchymal Sema3d guides outgrowth of the common cardinal vein via repulsion and signals through PlexinD1. 27799363
2015-07-04 11:36:00 Plxnd1 is a novel regulator of VAT growth, body fat distribution, and insulin sensitivity in both zebrafish and humans 25831505
2011-03-19 10:13:00 Somite expression of known vascular guidance cues, efnb2, sema3a2, and plexinD1 are disrupted, suggesting that the inter-somitic vessel vascular phenotype is due to disruption of these cues. 21038448
2010-01-21 00:00:00 Loss of plxnB2 results in delayed ISV sprouting identical to that seen in sema3e morphants, while loss of plexinD1 in out of bounds (obd) mutants results in precocious ISV sprouting. 19422817

名称对应

Type IDs
Synonymous zgc:77379
Gene
UniProtKB-ID: Q6DSU3_DANRE
UniprotKB: Q6DSU3
UniParc: UPI00003BF8F1
EMBL: AY648302
KO: dre:402998
Nucleutide sequences
EMBL-CDS: AAT64905.1
Protein sequencees
RefSeq: NP_991260.2
Others
UniRef100: UniRef100_Q6DSU3
UniRef90: UniRef90_Q6DSU3
UniRef50: UniRef50_Q3UH93
UniGene: Dr.103153

全选

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研究热度

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