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40260 Psn

40260

Psn

Presenilin

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Presenilin

研究结论

Date Results Publications
2017-10-21 12:48:00 Psn is required for neuronal survival during aging and normal lifespan. 28495961
2014-03-22 10:10:00 findings suggest that a normal function of presenilin (PS)is to repress kinesin-1 and dynein motor activity during axonal transport of amyloid precursor protein (APP) vesicles; perturbations of APP/PS transport could contribute to early neuropathology observed in Alzheimer's Diseaseprecursor protein (APP) vesicles 23710041
2013-12-14 12:05:00 a conserved role for presenilin in mediating copper uptake 23667524
2013-06-29 12:27:00 The interaction of Sanpodo with Presenilin, a component of the gamma-secretase complex, is required for Notch activation. 23609534
2012-10-13 11:08:00 Consistent with its role in Psn processing, Hbs genetically interacts with the Drosophila beta-amyloid protein precursor-like (Appl) protein. 22814602

名称对应

Type IDs
Synonymous 0480/15, 0493/14, 493/14, CG18803, CG5868, DPS, DPsn, DmPS, Dmel\CG18803, Dps, DrosPS, PS, PS1, PSN, dPsn, l(3)77CDb, l(3)S048015a, l(3)S049314, l(3)S049314a, pres, psn
Gene
UniProtKB-ID: PSN_DROME, M9PFS2_DROME, B7Z090_DROME, M9PG70_DROME
UniprotKB: O02194, M9PFS2, B7Z090, M9PG70
UniParc: UPI00001BBB15, UPI0000124722, UPI000002B1C4
EMBL: AF017026, AF017024, U77934, AF084184, AF017025, AY061316, AE014296, AF093402, U78084
EnsemblGenome: FBgn0284421
KO: dme:Dmel_CG18803
Nucleutide sequences
EMBL-CDS: AAB53369.1, AAD52707.1, AAD52708.1, AAB61139.1, AAD01611.1, AAL28864.1, AAD01610.1, AAC33128.1, AAF51598.1, AAC33129.1, AAN12132.1, AAD01612.1, AGB94803.1, ACL83343.1, AGB94804.1
Gene_ORFName: CG18803, CG18803, Dmel_CG18803, Dmel_CG18803, CG18803, CG18803, Dmel_CG18803
EnsemblGenome_TRS: FBtr0078193, FBtr0078192, FBtr0333479, FBtr0114517, FBtr0333478, FBtr0333478, FBtr0078193, FBtr0114517, FBtr0333479, FBtr0078192
Protein sequencees
EnsemblGenome_PRO: FBpp0305666, FBpp0113009, FBpp0305665, FBpp0077851, FBpp0077850, FBpp0077851, FBpp0305665, FBpp0113009, FBpp0077850, FBpp0305666
RefSeq: NP_001262110.1, NP_001137988.1, NP_524184.1, NP_001262111.1, NP_730535.1
Others
UniRef100: UniRef100_B7Z090, UniRef100_M9PFS2, UniRef100_O02194
UniRef90: UniRef90_O02194
UniRef50: UniRef50_O02194
UniGene: Dm.3254

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研究热度

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