| Type | Description |
|---|---|
| Definition | gigas |
| Date | Results | Publications |
|---|---|---|
| 2017-06-10 12:44:00 | our data identify the eIF4F complex as an important upstream regulator of TORC1, which acts via TSC2 to inactivate TORC1 upon withdrawal of amino acids | 26988032 |
| 2016-01-16 12:23:00 | Results identified Ser1338 in Drosophila TSC2 as the site for AMPK phosphorylation. Its mutation diminished the function of TSC2 in suppressing mTORC1-dependent cell growth in Drosophila wing epithelium. | 25826530 |
| 2014-04-26 10:15:00 | hyperactivation of TORC1 following the loss of TSC1/2 is detrimental to stem cell maintenance and multiple lineage differentiation in the Drosophila intestinal stem cell lineage, a mechanism that could be conserved in other stem cell lineages | 23843608 |
| 2013-11-30 10:47:00 | Data indicate that TORC1 activation by PVR involves Tsc1/Tsc2. | 23878397 |
| 2013-11-02 11:08:00 | deregulation of TORC1 induces activation of JNK, indicate that multiple cellular stresses are induced and contribute to the synthetic-lethal interactions between RB and TSC1/TSC2 inactivation. | 23447678 |
| Type | IDs |
|---|---|
| Synonymous | 6975, C1, CG6975, Dmel\CG6975, FBpp0074588, Gigas, ME 109, TSC2, Tsc2, Tsc2/gig, dTSC2, dTsc2, gig/Tsc2, gig, Tsc2, l(3)109, tsc2 |
| Gene |
UniProtKB-ID:
M9PD17_DROME,
Q9VW83_DROME
UniprotKB:
M9PD17,
Q9VW83
UniParc:
UPI0002943CE5,
UPI0000076411
EMBL:
AE014296
EnsemblGenome:
FBgn0005198
KO:
dme:Dmel_CG6975
|
| Nucleutide sequences |
EMBL-CDS:
AGB94782.1,
AAF49066.1
Gene_ORFName:
CG6975,
Dmel_CG6975,
Dmel_CG6975,
CG6975
EnsemblGenome_TRS:
FBtr0332690,
FBtr0074819
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0304936,
FBpp0074588
RefSeq:
NP_524177.1,
NP_001262089.1
|
| Others |
UniRef100:
UniRef100_Q9VW83,
UniRef100_M9PD17
UniRef90:
UniRef90_Q9VW83
UniRef50:
UniRef50_Q9VW83
UniGene:
Dm.2047
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员