| Type | Description |
|---|---|
| Definition | ADP ribosylation factor like GTPase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 10:45:00 | we uncover ARL2 as a novel candidate gene for MRCS syndrome and suggest a mitochondria-related mechanism of the first ARL2 variant through site-directed mutagenesis studies. | 30945270 |
| 2019-09-14 12:48:00 | Results suggest that ELMOD2 is functioning as an effector downstream of ARL2 and upstream of the mitofusins to promote mitochondrial fusion. Data provide insights into the pathway by which mitochondrial fusion is regulated in the cell. | 30865555 |
| 2019-01-19 11:48:00 | Decreased ARL2 expression level was clinically correlated to the higher grades and poorer outcomes of glioma patients. ARL2 overexpression attenuated the proliferation, clone formation, migration, invasive and tumorigenic capabilities of glioma cells by regulating the expression of receptor tyrosine kinase AXL. | 29843637 |
| 2018-08-04 10:48:00 | High ARL2 expression is associated with Osteosarcoma. | 29265919 |
| 2017-12-02 10:54:00 | conclude that the TBCD*ARL2*beta-tubulin complex represents a functional intermediate in the beta-tubulin folding pathway whose activity is regulated by the cycling of nucleotides on ARL2 | 28970104 |
| Type | IDs |
|---|---|
| Synonymous | ARFL2 |
| Gene |
UniProtKB-ID:
ARL2_HUMAN,
Q53YD8_HUMAN
UniprotKB:
P36404,
Q53YD8
UniParc:
UPI000013CBFD,
UPI00001FAB10
EMBL:
AF493888,
CN338497,
AK223502,
CH471076,
AP000436,
BC002530,
BT006674,
L13687
Ensembl:
ENSG00000213465
KO:
hsa:402
|
| Nucleutide sequences |
EMBL-CDS:
AAM12602.1,
EAW74333.1,
AAC37606.1,
AAH02530.1,
EAW74332.1,
AAP35320.1,
BAD97222.1
Gene_ORFName:
hCG_23373
Ensembl_TRS:
ENST00000246747,
ENST00000529384,
ENST00000533729
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000432971,
ENSP00000436021,
ENSP00000246747
RefSeq:
NP_001186674.1,
NP_001658.2
|
| Others |
UniRef100:
UniRef100_P36404
UniRef90:
UniRef90_P36404
UniRef50:
UniRef50_P36404
UniGene:
Hs.502836
CCDS:
CCDS8088.1,
CCDS55770.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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