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40170 Mi-2

40170

Mi-2

Mi-2

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Mi-2

研究结论

Date Results Publications
2020-08-22 15:28:00 The Mi-2 nucleosome remodeler and the Rpd3 histone deacetylase are involved in piRNA-guided heterochromatin formation. 32499524
2020-04-11 12:42:00 Mi-2/NuRD complex protects stem cell progeny from mitogenic Notch signaling. 30694174
2019-11-09 13:05:00 Results of genetic interaction analyses revealed that Mi-2 and Caf1/p55, components of the Nucleosome Remodeling and Deacetylase (NuRD) complex, genetically antagonize the role of DREF in germline stem cell maintenance. Taken together, these data suggest that DREF contributes to intrinsic components of the germline stem cell regulatory network that maintains competence to self-renew. 31226128
2018-12-22 11:09:00 Genetic experiments in Drosophila demonstrate that expression of cancer-derived dMi-2 mutants misregulates differentiation of epithelial wing structures and produces phenotypes that correlate with their nucleosome remodelling properties. 29844320
2018-12-22 10:59:00 EcR and dMi-2 form a complex that is devoid of Ultraspiracle. Unexpectedly, EcR contacts the dMi-2 ATPase domain and increases the efficiency of dMi-2-mediated nucleosome remodelling 28378812

名称对应

Type IDs
Synonymous 0006/06, 0854/01, CG8103, Chd4, Dm-Mi-2, Dmel\CG8103, M-i2, MI-2, MI2, Mi 2, Mi2, Pha, dMI-2, dMi, dMi-2, dMi2, hip76, l(3)01058, l(3)76BDe, l(3)A154.3M3, l(3)L1243, l(3)S000606, l(3)S085401, l(3)j3D4, pha
Gene
UniProtKB-ID: CHDM_DROME, M9PIA6_DROME, Q59E34_DROME, E1JI46_DROME
UniprotKB: O97159, M9PIA6, Q59E34, E1JI46
UniParc: UPI0002943196, UPI00000072ED, UPI00001E1CD3
EMBL: AF119716, AY113368, AE014296
EnsemblGenome: FBgn0262519
KO: dme:Dmel_CG8103
Nucleutide sequences
EMBL-CDS: AAF49099.2, AAD17276.1, AAM29373.1, AGB94771.1, AAX52739.1, ACZ94747.1
Gene_ORFName: CG8103, Dmel_CG8103, CG8103, Dmel_CG8103, CG8103, Dmel_CG8103, CG8103
EnsemblGenome_TRS: FBtr0302046, FBtr0074919, FBtr0332152, FBtr0100394, FBtr0074919, FBtr0302046
Protein sequencees
EnsemblGenome_PRO: FBpp0291256, FBpp0074688, FBpp0304462, FBpp0099808, FBpp0291256, FBpp0074688
RefSeq: NP_001014591.1, NP_649154.2, NP_001163476.1, NP_001262078.1
Others
UniRef100: UniRef100_M9PIA6, UniRef100_Q59E34, UniRef100_O97159
UniRef90: UniRef90_O97159
UniRef50: UniRef50_O97159
UniGene: Dm.28317

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研究热度

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