例如:"NBL1", "4681", "drought"
收藏
40141 asf1

40141

asf1

anti-silencing factor 1

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition anti-silencing factor 1

研究结论

Date Results Publications
2018-10-06 10:51:00 ASF1 is critically required to load H3.3-H4 dimers on the HIRA complex prior to histone deposition on paternal DNA. This separation of tasks could optimize the rapid assembly of paternal chromatin within the gigantic volume of the egg cell. In contrast, ASF1 is surprisingly dispensable for the amplification of cleavage nuclei, although chromatin integrity is likely compromised in asf1 knocked-down embryos. 29751847
2017-09-16 12:10:00 DLP and ASF1 are part of a predeposition complex, which is recruited by XNP and is necessary to prevent DNA exposure in the nucleus. 28320872
2010-03-22 11:21:00 ASF1 cellular levels are tightly controlled by distinct pathways and provide a molecular mechanism for post-translational regulation of dASF1 and hASF1a by TLK kinases. 20016786
2010-01-21 00:00:00 dASF1 has a direct role in modifying chromatin structure during DNA replication and this function of dASF1 is important for the processivity of the replication machinery. 16396992
2010-01-21 00:00:00 Histone chaperones ASF1 and NAP1 differentially modulate removal of active histone marks by LID-RPD3 complexes during NOTCH silencing. 19782028

名称对应

Type IDs
Synonymous ASF-1, ASF1, Asf1, CG9383, Dmel\CG9383, dASF/SF2, dASF1, dAsf1, l(3)76BDq
Gene
UniProtKB-ID: ASF1_DROME, C0MIY4_DROME
UniprotKB: Q9V464, C0MIY4
UniParc: UPI000000C4D8
EMBL: AE014296, FM245312, FM245310, FM245306, FM245307, AM294238, BT004869, FM245314, AM294246, FM245309, AM294236, FM245311, AM294237, AF189278, AM294245, FM245308, FM245316, FM245313, AM294241, FM245317, AM294244, AM294239, AM294240, AM294243, AM294242, FM245315
EnsemblGenome: FBgn0029094
KO: dme:Dmel_CG9383
Nucleutide sequences
EMBL-CDS: CAL26150.1, CAL26148.1, CAL26149.1, CAL26141.1, AAO45225.1, CAL26143.1, CAL26142.1, AAF49131.1, CAL26144.1, AAF15354.1, CAL26146.1, CAL26147.1, CAL26145.1, CAL26140.1, CAR93239.1, CAR93242.1, CAR93240.1, ADV37567.1, CAR93233.1, CAR93238.1, CAR93232.1, CAR93235.1, CAR93236.1, CAR93237.1, CAR93241.1, CAR93243.1, CAR93234.1
Gene_ORFName: CG9383, CG9383, Dmel_CG9383
EnsemblGenome_TRS: FBtr0074947, FBtr0302381, FBtr0074947, FBtr0302381
Protein sequencees
EnsemblGenome_PRO: FBpp0074715, FBpp0291576, FBpp0291576, FBpp0074715
RefSeq: NP_001189131.1, NP_524163.1
Others
UniRef100: UniRef100_Q9V464
UniRef90: UniRef90_Q9V464
UniRef50: UniRef50_Q9V464
UniGene: Dm.2521

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员