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40090 fz2

40090

fz2

frizzled 2

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition frizzled 2

研究结论

Date Results Publications
2020-06-27 11:56:00 cells located outside the reach of extracellular Wg depend on the Frizzled2 receptor to maintain signaling. Frizzled2 expression is increased in the absence of Wg secretion and is required to maintain signaling and cell survival in NRT-wg wing discs. 31399474
2016-01-16 10:48:00 Maturation of a central brain flight circuit in Drosophila requires Fz2 and Ca2+ signaling. 25955970
2014-10-18 12:45:00 The heterotrimeric G protein Go functions as a transducer of Wingless-Frizzled 2 signaling in the synapse and Ankyrin 2 as a target of Go signaling required for neuromuscular junction formation 25139856
2012-11-24 11:01:00 Study finds that C-terminal fragments of the Wg receptor DFz2 accumulate in nuclear foci in association with large RNA granules localizing to the space between the inner & and outer nuclear membranes; granules are found at of inner membrane invaginations, are bounded by LamC, and can be seen leaving the nucleus. 22579286
2011-08-27 12:17:00 Knockdown of Tc-fz1 alone interfered with the formation of the proximo-distal and the dorso-ventral axes during leg development, whereas no effect was observed with single Tc-fz2 or Tc-fz4 knockdowns. 21652652

名称对应

Type IDs
Synonymous CG9739, D-Fz2, D-fz2, DFZ2, DFz-2, DFz2, DFz2C, Dfrz2, Dfz2, Dfz[[2]], Dm Fz2, Dmel\CG9739, FZ2, Fz2, dFz2, dfz(2), dfz2, dfz2r, frz2, fz-2
Gene
UniProtKB-ID: FRIZ2_DROME, B7Z072_DROME, M9PFW3_DROME
UniprotKB: Q9VVX3, B7Z072, M9PFW3
UniParc: UPI00001E1C94, UPI00001249D1
EMBL: BT023785, AE014296, U65589
EnsemblGenome: FBgn0016797
KO: dme:Dmel_CG9739
Nucleutide sequences
EMBL-CDS: AAZ41794.1, ABW08569.1, AAC47273.1, AAF49184.1, AGB94729.1, ACL83326.1, AGB94731.1, AGB94730.1
Gene_ORFName: CG9739, CG9739, Dmel_CG9739, CG9739, Dmel_CG9739
EnsemblGenome_TRS: FBtr0330194, FBtr0075029, FBtr0075028, FBtr0332735, FBtr0112890, FBtr0299586, FBtr0075028, FBtr0112890, FBtr0299586, FBtr0330194, FBtr0075029, FBtr0332735, FBtr0330195
Protein sequencees
EnsemblGenome_PRO: FBpp0304981, FBpp0111803, FBpp0303227, FBpp0288861, FBpp0074795, FBpp0074796, FBpp0288861, FBpp0074795, FBpp0111803, FBpp0074796, FBpp0303227, FBpp0304981, FBpp0303228
RefSeq: NP_001137971.1, NP_001097643.1, NP_730389.1, NP_001262036.1, NP_001262038.1, NP_001262037.1, NP_524155.1
Others
UniRef100: UniRef100_Q9VVX3
UniRef90: UniRef90_Q9VVX3
UniRef50: UniRef50_Q9VVX3
UniGene: Dm.2524

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