| Type | Description |
|---|---|
| Definition | Mitogen-activated protein kinase phosphatase 3 |
| Date | Results | Publications |
|---|---|---|
| 2014-08-23 10:33:00 | We show that Tay bridge antagonizes EGFR signalling in the Drosophila melanogaster wing disc and other tissues, and that the protein interacts with both Erk and Mkp3 | 24348264 |
| 2010-01-21 00:00:00 | Study suggests that Mkp3 constitutes a conserved negative feedback loop on the activity of the Ras/ERK signaling pathway. | 15704110 |
| 2010-01-21 00:00:00 | MKP-3 is critically involved in cell differentiation, proliferation, and gene expression by suppressing the Ras/ERK pathway, specifically binding to ERK via the N-terminal ERK-binding domain of MKP-3. | 14701731 |
| 2010-01-21 00:00:00 | Drosophila ERK specifically regulates DMKP-3 in terms of its enzyme activity and protein stability esssential for regulation. | 15033693 |
| Type | IDs |
|---|---|
| Synonymous | CG14080, CG14081, DMKP-3, Dmel\CG14080, Dmkp3, MKP3, dMKP3, mkp-3, mkp3 |
| Gene |
UniProtKB-ID:
DUSK3_DROME,
M9PFW0_DROME,
M9PG13_DROME
UniprotKB:
Q9VVW5,
M9PFW0,
M9PG13
UniParc:
UPI000007B0BE,
UPI00001E1C8E,
UPI000008124D
EMBL:
AY043264,
AY060472,
AE014296,
BT003536
EnsemblGenome:
FBgn0036844
KO:
dme:Dmel_CG14080
|
| Nucleutide sequences |
EMBL-CDS:
AAO39540.1,
AAF49192.2,
AAF49193.2,
AAL25511.1,
AAK85311.1,
AGB94725.1,
AGB94724.1
Gene_ORFName:
CG14080,
Dmel_CG14080,
CG14080,
Dmel_CG14080,
CG14080
EnsemblGenome_TRS:
FBtr0075036,
FBtr0075035,
FBtr0333220,
FBtr0075035,
FBtr0333220,
FBtr0330089
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0074803,
FBpp0305422,
FBpp0074802,
FBpp0074802,
FBpp0305422,
FBpp0303122
RefSeq:
NP_730385.1,
NP_001262032.1,
NP_649087.1,
NP_001262031.1
|
| Others |
UniRef100:
UniRef100_Q9VVW5
UniRef90:
UniRef90_Q9VVW5
UniRef50:
UniRef50_Q9VVW5
UniGene:
Dm.3967
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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