| Type | Description |
|---|---|
| Definition | sialic acid binding Ig like lectin 16 (gene/pseudogene) |
| Date | Results | Publications |
|---|---|---|
| 2017-07-15 10:33:00 | The authors demonstrated that the human-specific pathogen Escherichia coli K1 uses its polysialic acid capsule as a molecular mimic to engage Siglec-11 and escape killing. In contrast, engagement of the activating counterpart Siglec-16 increases elimination of bacteria. | 28100677 |
| 2010-01-21 00:00:00 | SIGLEC16 encodes a DAP12-associated receptor expressed in macrophages that evolved from its inhibitory counterpart SIGLEC11 and has functional and non-functional alleles in humans. | 18629938 |
| Type | IDs |
|---|---|
| Synonymous | SIGLECP16, Siglec-P16 |
| Gene | |
| Nucleutide sequences | |
| Protein sequencees |
RefSeq:
NP_001335293.2
|
| Others |
UniGene:
Hs.568076,
Hs.738007
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 28100677 |
Paired Siglec receptors generate opposite inflammatory responses to a human-specific pathogen. EMBO J Flavio Schwarz , Corinna S Landig , Shoib Siddiqui , Ismael Secundino , Joshua Olson , Nissi Varki , Victor Nizet , Ajit Varki |
2017-03-15 | - |
| 22383531 |
Evolution of siglec-11 and siglec-16 genes in hominins. Mol. Biol. Evol. Xiaoxia Wang , Nivedita Mitra , Pedro Cruz , Liwen Deng , NISC Comparative Sequencing Program , Nissi Varki , Takashi Angata , Eric D Green , Jim Mullikin , Toshiyuki Hayakawa , Ajit Varki |
2012-08-01 |
SIGLEC16
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 18629938 |
Eur J Immunol Huan Cao , Ursula Lakner , Bernard de Bono , James A Traherne , John Trowsdale , Alexander D Barrow |
2008-08-01 | - |
| 16151003 |
A human-specific gene in microglia. Science Toshiyuki Hayakawa , Takashi Angata , Amanda L Lewis , Tarjei S Mikkelsen , Nissi M Varki , Ajit Varki |
2005-09-09 |
SIGLEC11
|
| 15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
| 15057824 |
The DNA sequence and biology of human chromosome 19. Nature Jane Grimwood , Laurie A Gordon , Anne Olsen , Astrid Terry , Jeremy Schmutz , Jane Lamerdin , Uffe Hellsten , David Goodstein , Olivier Couronne , Mary Tran-Gyamfi , Andrea Aerts , Michael Altherr , Linda Ashworth , Eva Bajorek , Stacey Black , Elbert Branscomb , Sean Caenepeel , Anthony Carrano , Chenier Caoile , Yee Man Chan , Mari Christensen , Catherine A Cleland , Alex Copeland , Eileen Dalin , Paramvir Dehal , Mirian Denys , John C Detter , Julio Escobar , Dave Flowers , Dea Fotopulos , Carmen Garcia , Anca M Georgescu , Tijana Glavina , Maria Gomez , Eidelyn Gonzales , Matthew Groza , Nancy Hammon , Trevor Hawkins , Lauren Haydu , Isaac Ho , Wayne Huang , Sanjay Israni , Jamie Jett , Kristen Kadner , Heather Kimball , Arthur Kobayashi , Vladimer Larionov , Sun-Hee Leem , Frederick Lopez , Yunian Lou , Steve Lowry , Stephanie Malfatti , Diego Martinez , Paula McCready , Catherine Medina , Jenna Morgan , Kathryn Nelson , Matt Nolan , Ivan Ovcharenko , Sam Pitluck , Martin Pollard , Anthony P Popkie , Paul Predki , Glenda Quan , Lucia Ramirez , Sam Rash , James Retterer , Alex Rodriguez , Stephanine Rogers , Asaf Salamov , Angelica Salazar , Xinwei She , Doug Smith , Tom Slezak , Victor Solovyev , Nina Thayer , Hope Tice , Ming Tsai , Anna Ustaszewska , Nu Vo , Mark Wagner , Jeremy Wheeler , Kevin Wu , Gary Xie , Joan Yang , Inna Dubchak , Terrence S Furey , Pieter DeJong , Mark Dickson , David Gordon , Evan E Eichler , Len A Pennacchio , Paul Richardson , Lisa Stubbs , Daniel S Rokhsar , Richard M Myers , Edward M Rubin , Susan M Lucas |
2004-04-01 |
ZGLP1,
C19orf71,
ZNF725P,
TMEM221,
SBK3,
SNRPGP15,
BSPH1,
KIR2DS2,
LOC100134317,
ERICH4,
MEF2B,
ZNF729,
ZNF861P,
GFY,
ZNF865,
ERVS71-1,
SUGP2,
EBI3,
AKAP8,
HMG20B,
KLF1,
CERS1,
CEACAM7,
CEACAM8,
UQCR11,
KLK11,
TMED1,
UPK1A,
KLK8,
PNKP,
COPE,
CIRBP,
TBCB,
ARHGAP33,
CKM,
GRIN3B,
CLC,
CCDC159,
MOB3A,
GIPC3,
OR1I1,
HSPB6,
COMP,
COX6B1,
COX7A1,
CSNK1G2,
NCAN,
ZNRF4,
ZNF98,
DIRAS1,
CYP2B6,
AP2A1,
ZNF550,
ZNF780B,
AES,
DMWD,
DNASE2,
DNM2,
DNMT1,
ARID3A,
EFNA2,
NLRP7,
ERF,
FBL,
ETV2,
FARSA,
MAST1,
KDM4B,
MAST3,
CIC,
CRTC1,
PIP5K1C,
ETHE1,
BRD4,
FPR1,
FPR2,
FKBP8,
CBARP,
C19orf38,
SYCE2,
SHC2,
GAMT,
KLK13,
PRPF31,
GAPDHS,
OR7A17,
GCDH,
OR10H3,
OR10H2,
OR10H1,
GDF1,
OR7E24,
OR7C2,
OR7A5,
OR7C1,
AMH,
GIPR,
LYPD3,
TJP3
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 11986327 |
J Biol Chem Takashi Angata , Sheena C Kerr , David R Greaves , Nissi M Varki , Paul R Crocker , Ajit Varki |
2002-07-05 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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目前还没有研究热点人员