| Type | Description |
|---|---|
| Definition | serine protease 57 |
| Date | Results | Publications |
|---|---|---|
| 2015-05-23 10:05:00 | Structural insights in to substrate recognition by the trypsin-fold protease NSP4. | 25156428 |
| 2015-01-20 18:00:00 | cathepsin C was identified as the activator of NSP4 in vivo, as cathepsin C deficiency resulted in a complete absence of NSP4 in a Papillon-Lefevre patient | 23904161 |
| Type | IDs |
|---|---|
| Synonymous | NSP4, PRSSL1, UNQ782 |
| Gene |
UniProtKB-ID:
PRS57_HUMAN,
B7ZMF6_HUMAN
UniprotKB:
Q6UWY2,
B7ZMF6
UniParc:
UPI000022AA4D,
UPI000189A90A
EMBL:
AY358594,
AC112708,
BC137161,
AC004156,
BC144505
Ensembl:
ENSG00000185198
KO:
hsa:400668
|
| Nucleutide sequences |
EMBL-CDS:
AAQ88957.1,
AAI37162.1,
AAI44506.1
Gene_ORFName:
UNQ782/PRO1599
Ensembl_TRS:
ENST00000613411
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000482358
RefSeq:
NP_999875.2,
NP_001295138.2
|
| Others |
UniRef100:
UniRef100_Q6UWY2,
UniRef100_B7ZMF6
UniRef90:
UniRef90_Q6UWY2
UniRef50:
UniRef50_Q6UWY2
UniGene:
Hs.245146
CCDS:
CCDS12041.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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