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4004 LMO1

4004

LMO1

LIM domain only 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition LIM domain only 1

研究结论

Date Results Publications
2020-02-29 12:24:00 ASCL1 and LMO1 directly regulate the expression of CRC genes, indicating that ASCL1 is a member and LMO1 is a coregulator of the ADRN neuroblastoma core regulatory circuitry. 31819055
2018-12-01 10:05:00 Target genes of the LMO1-regulated microRNAs and their relevant pathways may be a potential therapeutic targe 30194082
2018-02-10 10:35:00 IKZF1 rs10235796 C allele, IKZF1 rs6964969A>G, CDKN2A rs3731246 G>C, and CDKN2A rs3731246 C allele were signi fi cantly associated with Acute Lymphoblastic Leukemia in Yemenis of Arab-Asian descent. Borderline association found in IKZF1 rs4132601 T>G variant. No associations found with LMO1 rs442264; rs3794012; rs4237770 28768142
2017-12-16 10:25:00 These results suggested that LMO1 gene rs110419 A > G polymorphism may contribute to protection against neuroblastoma 27009839
2017-10-28 10:39:00 A C-to-T single nucleotide transition occurs as a somatic mutation in noncoding sequences 4 kb upstream of the transcriptional start site of the LMO1 oncogene in primary samples from patients with T-cell acute lymphoblastic leukaemia. This conforms to an APOBEC-like cytidine deaminase mutational signature and a new MYB binding site driving high levels of LMO1 expression. 28260788

名称对应

Type IDs
Synonymous RBTN1, RHOM1, TTG1
Gene
UniProtKB-ID: RBTN1_HUMAN, E9PK83_HUMAN
UniprotKB: P25800, E9PK83
UniParc: UPI00001F9CC5, UPI0000133883, UPI0001F77EFE
EMBL: BC039512, AJ277662, M26682, BC069673, BC096056, BC096057, BC069752, AC091013, BC069793
Ensembl: ENSG00000166407
KO: hsa:4004
Nucleutide sequences
EMBL-CDS: AAH96057.1, AAH69673.1, AAH69793.1, AAA36819.1, AAH69752.1, AAH39512.1, CAC14587.1, AAH96056.1
Ensembl_TRS: ENST00000428101, ENST00000335790, ENST00000534484
Protein sequencees
Ensembl_PRO: ENSP00000338207, ENSP00000404538, ENSP00000435456
RefSeq: XP_011518402.1, XP_011518400.1, XP_011518401.1, NP_002306.1, NP_001257357.1, XP_006718291.1
Others
UniRef100: UniRef100_P25800, UniRef100_E9PK83
UniRef90: UniRef90_P25800, UniRef90_E9PK83
UniRef50: UniRef50_E9PK83, UniRef50_P25800
UniGene: Hs.654426
CCDS: CCDS44534.1, CCDS58118.1

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