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40030 not

40030

not

non-stop

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition non-stop

研究结论

Date Results Publications
2020-03-21 11:19:00 The data indicate that the germline-specific nuclear functions of the Drosophila Ccr4-Not complex involve the repression of especially dangerous active transposable elements as well as the nuclear biogenesis of telomeric transcripts. 31724732
2020-02-01 11:27:00 Atxn7 amino terminus anchors Non-stop, a deubiquitinase, to the SAGA chromatin remodeling complex. There, Non-stop countered polyubiquitination and proteasomal degradation of Arp2/3 and WAVE regulatory complex (WRC) subunit SCAR. 31348003
2015-10-10 11:38:00 Loss of Ataxin-7 results in a toxic gain of activity of the Non-stop deubiquitinase. 25483136
2010-01-21 00:00:00 Data establish that Nonstop actually functions as an ubiquitin protease to control the levels of ubiquitinated histone H2B in flies. We further establish that Nonstop is the functional homolog of yeast Ubp8 18188155
2010-01-21 00:00:00 3 additional subunits of TFTC/STAGA (dSgf11, non-stop, & en(y)2) help form the deubiquitination module. This module is an enhancer of position effect variegation in Drosophila. 18206972

名称对应

Type IDs
Synonymous CG4166, Dmel\CG4166, NOT, Nonstop, Not, Q9VVR1, UBP8, USP22, Upb8, anon-WO0257455.9, i155, l(3)02069, l(3)j9A6, nonstop
Gene
UniProtKB-ID: NOT_DROME
UniprotKB: Q9VVR1
UniParc: UPI0001914976
EMBL: AY058707, AF179590, AE014296
EnsemblGenome: FBgn0013717
KO: dme:Dmel_CG4166
Nucleutide sequences
EMBL-CDS: AAD53181.1, AAF49249.2, AHN58131.1, AAL13936.1
Gene_ORFName: CG4166
EnsemblGenome_TRS: FBtr0290259, FBtr0346438
Protein sequencees
EnsemblGenome_PRO: FBpp0288698, FBpp0312097
RefSeq: NP_001287106.1, NP_524140.2
Others
UniRef100: UniRef100_Q9VVR1
UniRef90: UniRef90_Q9VVR1
UniRef50: UniRef50_Q9UPT9
UniGene: Dm.2731

全选

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