| Type | Description |
|---|---|
| Definition | SHC adaptor protein 4 |
| Date | Results | Publications |
|---|---|---|
| 2018-05-05 10:05:00 | ShcD appears to possess several molecular permutations that actively govern the EGFR, which may have implications in development and disease. | 28724758 |
| 2017-06-03 11:38:00 | ShcD binds to active Ret, TrkA, and TrkB neurotrophic factor receptors predominantly via its phosphotyrosine-binding (PTB) domain. | 28213521 |
| 2014-11-08 11:15:00 | The ShcD signaling adaptor facilitates ligand-independent phosphorylation of the EGF receptor. | 24430869 |
| 2014-06-28 11:47:00 | ShcD can exist within the nucleus, and its CH2 domain has a critical role in nuclear export of ShcD. | 24036217 |
| 2012-11-17 10:15:00 | ShcD binds to TrkC in a kinase-activity-dependent manner through its PTB and SH2 domains. | 20078941 |
| Type | IDs |
|---|---|
| Synonymous | RaLP, SHCD |
| Gene |
UniProtKB-ID:
SHC4_HUMAN
UniprotKB:
Q6S5L8
UniParc:
UPI00001D6961,
UPI00001B00C8
EMBL:
AY358250,
AY464565,
BC033907
Ensembl:
ENSG00000185634
KO:
hsa:399694
|
| Nucleutide sequences |
EMBL-CDS:
AAR19363.1,
AAQ88617.1,
AAH33907.1
Gene_ORFName:
UNQ6438/PRO21364
Ensembl_TRS:
ENST00000396535,
ENST00000332408
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000329668,
ENSP00000379786
RefSeq:
XP_005254432.1,
NP_976224.3
|
| Others |
UniRef100:
UniRef100_Q6S5L8
UniRef90:
UniRef90_Q6S5L8
UniRef50:
UniRef50_Q6S5L8
UniGene:
Hs.642615
CCDS:
CCDS10130.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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