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399687 MYO18A

399687

MYO18A

myosin XVIIIA

protein-coding

Homo sapiens

基因描述

Type Description
Definition myosin XVIIIA

研究结论

Date Results Publications
2019-09-14 12:52:00 a high proportion of MYO18A is found in complex with GOLPH3 at the trans Golgi, where it functions to promote vesicle budding for Golgi-to-plasma membrane trafficking. 28942352
2017-07-15 10:34:00 Studies indicate that MYO18A is overexpressed in metastatic prostate cancer (PC-3) cells. 27528748
2014-04-26 13:05:00 Identification of the DNA-damage-induced Golgi response reveals an unexpected pathway through DNA-PK, GOLPH3, and MYO18A that regulates cell survival following DNA damage. 24485452
2014-01-04 13:17:00 PDZ module mediates direct binding of myosin-18A to GOLPH3, and this interaction in turn modulates the actin binding properties of the N-terminal extension. Thus, myosin-18A can act as an actin cross-linker with multiple regulatory modulators 23990465
2013-09-14 10:36:00 GOLPH3L differs critically from GOLPH3 in that it is largely unable to bind to MYO18A; data demonstrate that despite their similarities, unexpectedly, GOLPH3L antagonizes GOLPH3/MYO18A at the Golgi 23345592

名称对应

Type IDs
Synonymous MAJN, MYSPDZ, SP-R210, SPR210
Gene
UniProtKB-ID: MY18A_HUMAN, Q9NYE8_HUMAN, A0A024QZ63_HUMAN
UniprotKB: Q92614, Q9NYE8, A0A024QZ63
UniParc: UPI0000072252, UPI0000EE76F9, UPI0000167F32, UPI0000252194, UPI0000074364, UPI00001B5798
EMBL: AF252258, AY703984, CH471159, D86970, CR933614, AB177858, AB177860, BC039612
Ensembl: ENSG00000196535
KO: hsa:399687
Nucleutide sequences
EMBL-CDS: BAD66838.1, BAD66836.1, AAV80770.1, CAI45931.1, AAH39612.1, BAA13206.2, AAF70181.1, EAW51177.1, EAW51179.1
Gene_ORFName: hCG_27198
Ensembl_TRS: ENST00000527372, ENST00000531253, ENST00000533112
Protein sequencees
Ensembl_PRO: ENSP00000437073, ENSP00000434228, ENSP00000435932
RefSeq: NP_001333697.1, NP_510880.2, NP_001333695.1, NP_976063.1, NP_001333694.1, NP_001333696.1
Others
UniRef100: UniRef100_A0A024QZ63, UniRef100_B3KVF8, UniRef100_Q92614
UniRef90: UniRef90_A0A2K6N4N5, UniRef90_Q92614
UniRef50: UniRef50_A0A0D9R3X3, UniRef50_Q92614
UniGene: Hs.462590
CCDS: CCDS45642.1, CCDS86587.1, CCDS45641.1

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