| Type | Description |
|---|---|
| Definition | sodium channel, type IV, beta |
| Date | Results | Publications |
|---|---|---|
| 2020-09-05 13:53:00 | Effects of FGF14 and NaVbeta4 deletion on transient and resurgent Na current in cerebellar Purkinje neurons. | 31558566 |
| 2020-01-11 12:33:00 | Scn4b was involved in the acute hypnotic effects of ethanol and other sedatives. No evidence that Scn4b regulates ethanol consumption in mice was found. | 30817077 |
| 2017-08-26 12:48:00 | Data suggest that extracellular domains of Scn4b directly interact with each other in parallel homodimers that involve an intermolecular disulfide bond between unpaired Cys residues (Cys58) in loop connecting strands B and C and intermolecular hydrophobic and hydrogen-bonding interactions of N-terminal segments (Ser30-Val35); Scn4b homodimers appear to play role in cell-cell adhesion. | 28655765 |
| 2017-05-13 10:45:00 | Scn4b(-/-) animals have deficits in motor coordination and balance and that firing rates in Scn4b(-/-) Purkinje neurons are markedly attenuated. | 28423317 |
| 2011-10-08 11:25:00 | NaVbeta4 plays a blocking role that indicates the relative importance of different residues in inducing open-channel block. | 21832183 |
| Type | IDs |
|---|---|
| Synonymous | Gm1471 |
| Gene |
UniProtKB-ID:
SCN4B_MOUSE,
Q1MXF9_MOUSE
UniprotKB:
Q7M729,
Q1MXF9
UniParc:
UPI0000195D1F
EMBL:
AB118946,
AC122305,
AY669079,
AC122504,
BC139400,
BC139399,
BK001031
Ensembl:
ENSMUSG00000046480
KO:
mmu:399548
|
| Nucleutide sequences |
EMBL-CDS:
DAA01205.1,
AAU05394.1,
AAI39400.1,
BAE93689.1,
AAI39401.1
Ensembl_TRS:
ENSMUST00000060125
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000062507
RefSeq:
NP_001013408.1
|
| Others |
UniRef100:
UniRef100_Q7M729
UniRef90:
UniRef90_Q7M730
UniRef50:
UniRef50_Q7M730
UniGene:
Mm.335112
CCDS:
CCDS23130.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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