| Type | Description |
|---|---|
| Definition | lipase E, hormone sensitive type |
| Date | Results | Publications |
|---|---|---|
| 2020-03-07 12:16:00 | HSL regulates vitamin A metabolism in quiescent hepatic stellate cells. | 31150775 |
| 2017-10-21 10:40:00 | The homozygous null LIPE mutation could result in marked inhibition of lipolysis from some adipose tissue depots and thus may induce an extremely rare phenotype of MSL and partial lipodystrophy in adulthood associated with complications of insulin resistance, such as diabetes, hypertriglyceridemia and hepatic steatosis. | 27862896 |
| 2015-10-03 11:34:00 | Despite reductions in intramyocellular lipolysis and HSL expression, overexpression of HSL did not rescue defects in insulin action in skeletal myotubes from obese type 2 diabetic subjects. | 25819461 |
| 2015-04-04 11:48:00 | Identification of a homozygous nonsense variant p.Ala507fsTer563 in hormone sensitive lipase as the likely cause of the lipodystrophy phenotype in siblings. | 25475467 |
| 2014-06-28 13:23:00 | These findings indicate the physiological significance of HSL in adipocyte function and the regulation of systemic lipid and glucose homeostasis and underscore the severe metabolic consequences of impaired lipolysis. | 24848981 |
| Type | IDs |
|---|---|
| Synonymous | AOMS4, FPLD6, HSL, LHS |
| Gene |
UniProtKB-ID:
LIPS_HUMAN,
A8K8W7_HUMAN
UniprotKB:
Q05469,
A8K8W7
UniParc:
UPI000013CB66,
UPI00015DAA42,
UPI000012E71E
EMBL:
U40001,
AK292482,
DQ188033,
BC070041,
L11706
Ensembl:
ENSG00000079435
KO:
hsa:3991
|
| Nucleutide sequences |
EMBL-CDS:
AAA69810.1,
AAC50666.1,
ABA03168.1,
AAH70041.1,
BAF85171.1
Ensembl_TRS:
ENST00000244289
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000244289
RefSeq:
XP_005258996.2,
XP_005258994.1,
XP_006723281.1,
XP_016882299.1,
XP_024307282.1,
XP_005258997.1,
XP_005258995.1,
NP_005348.2
|
| Others |
UniRef100:
UniRef100_A8K8W7,
UniRef100_Q05469
UniRef90:
UniRef90_Q05469
UniRef50:
UniRef50_Q05469
UniGene:
Hs.656980
CCDS:
CCDS12607.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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