| Type | Description |
|---|---|
| Definition | Insulin-like peptide 8 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:36:00 | Tumour-derived Dilp8/INSL3 induces cancer anorexia by regulating feeding neuropeptides via Lgr3/8 in the brain. | 33558728 |
| 2020-05-30 12:02:00 | Early pupal stage is a novel Dilp8 mediated post-pupariation checkpoint; this provides further evidence for interorgan signaling during development, wherein a peripheral tissue influences the CNS driven endocrine function. | 31415125 |
| 2020-01-25 14:47:00 | demonstrates that RpS12, Xrp1, and Dilp8 form an independent regulatory module that ensures intra- and inter-organ growth coordination during development | 31006647 |
| 2020-01-11 10:41:00 | Activation of Dmp53 in the growth-depleted territory induces the expression of the Eiger, which activates the JNK stress signaling pathway. JNK-dependent expression of the systemic hormone dILP8 reduces the growth and final size of adjacent territories, the production of downstream of JNK and the apoptotic machinery act locally to regulate the proliferation of adjacent epithelial cells. | 31425511 |
| 2018-09-01 11:16:00 | These results indicate that growth coordination of organs is connected to their growth status through a feedback loop involving Hpo and Dilp8 signalling pathways. | 27874005 |
| Type | IDs |
|---|---|
| Synonymous | CG14059, DILP 8, DILP8, Dilp8, Dmel\CG14059, dILP-8, dILP8, dilp8, dlip8 |
| Gene |
UniProtKB-ID:
Q4V5V6_DROME
UniprotKB:
Q4V5V6
UniParc:
UPI000051D31A
EMBL:
BT022550,
BT022526,
AE014296,
KX531547
EnsemblGenome:
FBgn0036690
KO:
dme:Dmel_CG14059
|
| Nucleutide sequences |
EMBL-CDS:
AAY54966.1,
AAF49378.2,
AAY54942.1,
ANY27357.1
Gene_ORFName:
Dmel_CG14059,
CG14059
EnsemblGenome_TRS:
FBtr0290221
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0288660
RefSeq:
NP_648949.2
|
| Others |
UniRef100:
UniRef100_Q4V5V6
UniRef90:
UniRef90_Q4V5V6
UniRef50:
UniRef50_Q4V5V6
UniGene:
Dm.15206
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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