| Type | Description |
|---|---|
| Definition | DNA topoisomerase II alpha L homeolog |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 16:01:00 | Topoisomerase II Is Crucial for Fork Convergence during Vertebrate Replication Termination. | 31597101 |
| 2016-08-06 10:31:00 | MRN (Mre11, Rad50, and Nbs1) complex, CtIP, and BRCA1 are required for both the removal of Top2-DNA adducts and the subsequent resection of Top2-adducted DSB ends. | 26880199 |
| 2016-06-28 10:43:00 | TopoisomeraseIIalpha-C-terminal domain SUMOylation regulates the centromeric localization of Claspin. | 26131587 |
| 2013-11-02 10:57:00 | Topo IIalpha clamps trapped by ICRF-193 during but not after nuclear assembly block replication because topo IIalpha acts on unreplicated DNA before S phase but behind the forks during S phase. | 23757188 |
| 2011-01-08 11:05:00 | findings provide evidence for the regulation of TopoIIalpha activity on mitotic chromosomes by SUMOylation; propose a novel mechanism for regulation of centromeric DNA catenation during mitosis by PIASy-mediated SUMOylation of TopoIIalpha | 21079245 |
| Type | IDs |
|---|---|
| Synonymous | top2, top2a, tp2a |
| Gene |
UniProtKB-ID:
Q6INT0_XENLA
UniprotKB:
Q6INT0
UniParc:
UPI0000378232
EMBL:
CM004482,
BC072193
KO:
xla:398512
|
| Nucleutide sequences |
EMBL-CDS:
OCT62054.1,
AAH72193.1
Gene_ORFName:
XELAEV_18043138mg
|
| Protein sequencees |
RefSeq:
NP_001082502.1
|
| Others |
UniRef100:
UniRef100_Q6INT0
UniRef90:
UniRef90_Q6INT0
UniRef50:
UniRef50_P15348
UniGene:
Xl.45713
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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