| Type | Description |
|---|---|
| Definition | TPX2, microtubule-associated L homeolog |
| Date | Results | Publications |
|---|---|---|
| 2020-02-29 10:40:00 | By regulating the availability of the branching effectors TPX2, augmin and gamma-TuRC, combined with single-molecule observations, we show that first TPX2 is deposited on pre-existing microtubules (MTs), followed by binding of augmin/gamma-TuRC to result in the nucleation of branched MTs. | 31066674 |
| 2015-09-26 21:40:00 | This study identifies TPX2 as the only direct RanGTP target and NEDD1 as the only Aurora A substrate essential for the activation of the RanGTP-dependent microtubule nucleation pathway. | 25532896 |
| 2014-10-11 12:25:00 | TPX2 levels modulate spindle architecture through Eg5 in Xenopus oocyte extract. | 25070954 |
| 2010-06-28 11:42:00 | analysis of binding of the mitotic regulator TPX2 (target protein for Xenopus kinesin-like protein 2) to importin-alpha | 20335181 |
| 2010-01-21 00:00:00 | Here we identify G205 in Xenopus Aurora A as a key determinant of both intrinsic activity and regulation by TPX2. | 15908779 |
| Type | IDs |
|---|---|
| Synonymous | dil-2, dil2, hctp4, repp86, tpx2, tpx2-a, tpx2-b |
| Gene |
UniProtKB-ID:
TPX2A_XENLA,
A0A1L8ET96_XENLA
UniprotKB:
Q6NUF4,
A0A1L8ET96
UniParc:
UPI0000352AFF
EMBL:
AF244546,
CM004482,
BC068637
KO:
xla:398174
|
| Nucleutide sequences |
EMBL-CDS:
AAF81694.1,
AAH68637.1,
OCT62574.1
Gene_ORFName:
XELAEV_18043657mg
|
| Protein sequencees |
RefSeq:
XP_018089645.1,
XP_018089644.1,
XP_018089643.1,
NP_001082006.1,
XP_018089642.1
|
| Others |
UniRef100:
UniRef100_Q6NUF4
UniRef90:
UniRef90_Q6NUF4
UniRef50:
UniRef50_Q6NUF4
UniGene:
Xl.658
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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