| Type | Description |
|---|---|
| Definition | maternal embryonic leucine zipper kinase L homeolog |
| Date | Results | Publications |
|---|---|---|
| 2011-06-18 11:33:00 | Overexpression of xMELK leads to failure of cytokinesis and impairs accumulation RhoA- a pivotal regulator of cytokinesis. | 21378312 |
| 2010-01-21 00:00:00 | These results demonstrate the presence of a mitochondrial targeting signal at the N-terminus of the MC domain of MELK. This mitochondrial targeting signal was also functional in human HeLa cells.[MELK] | 17129738 |
| Type | IDs |
|---|---|
| Synonymous | Eg3, melk, xmelk |
| Gene |
UniProtKB-ID:
MELK_XENLA,
A0A1L8HXD2_XENLA
UniprotKB:
Q91821,
A0A1L8HXD2
UniParc:
UPI00000FE087
EMBL:
Z17205,
CM004466,
BC100161,
BC106635
KO:
xla:397927
|
| Nucleutide sequences |
EMBL-CDS:
AAI00162.1,
CAA78913.2,
AAI06636.1,
OCU00764.1
Gene_ORFName:
XELAEV_18006543mg
|
| Protein sequencees |
RefSeq:
NP_001081569.1,
XP_018087768.1
|
| Others |
UniRef100:
UniRef100_Q91821
UniRef90:
UniRef90_Q91821
UniRef50:
UniRef50_Q91821
UniGene:
Xl.7325
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32144273 |
Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation. Nat Commun Atsuya Nishiyama , Christopher B Mulholland , Sebastian Bultmann , Satomi Kori , Akinori Endo , Yasushi Saeki , Weihua Qin , Carina Trummer , Yoshie Chiba , Haruka Yokoyama , Soichiro Kumamoto , Toru Kawakami , Hironobu Hojo , Genta Nagae , Hiroyuki Aburatani , Keiji Tanaka , Kyohei Arita , Heinrich Leonhardt , Makoto Nakanishi |
2020-03-06 | - |
| 26673895 |
A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Elife Koray Kırlı , Samir Karaca , Heinz Jürgen Dehne , Matthias Samwer , Kuan Ting Pan , Christof Lenz , Henning Urlaub , Dirk Görlich |
2015-01-01 |
CHA1,
KRR1,
SRO9,
STE50,
RRP7,
RNQ1,
DCC1,
GBP2,
SAT4,
RVS161,
YCR016W,
PWP2,
SSK22,
SOL2,
PAT1,
YCR087C-A,
OCA4,
MOB2,
EPL1,
BUD27,
FRS2,
LOC1,
YFR016C,
LSB3,
RPL2A,
PHO4,
SAP155,
IRC6,
ENT4,
PRP19,
RIX7,
YLL032C,
FRA1,
ISA1,
SPA2,
PUF3,
RPL8B,
NOC3,
SSL1,
SSK1,
NSE1,
RLP24,
SDO1,
ADE16,
RPL15A,
STU2,
RPS0B,
FRS1,
BMT6,
KIN2,
HRT3,
REX3,
YLR108C,
CFT2,
MSL5,
ACE2,
STM1,
YLR157C-A,
APS1,
CBF5,
SWI6,
SKG3,
HCR1,
PWP1,
NOP56,
BUR2,
GPN3,
DBP9,
GCD7,
SGD1,
STE11,
NMD4,
RPS22B,
ROM2,
STP3,
IKI3,
REH1,
AFG2,
UTP21,
ATG17,
TUS1,
MAG2,
ATG23,
RPS1A,
FPR4,
PDP3,
CDC24,
RBG1,
FUN12,
MTW1,
PRP45,
MAK16,
ECM1,
GPB2,
VPS8,
KIN3,
CDC15,
YAT1,
WHI4
|
| 21378312 |
J. Cell. Sci. Yann Le Page , Isabelle Chartrain , Caroline Badouel , Jean-Pierre Tassan |
2011-03-15 |
melk
|
| 20420823 |
Exp. Cell Res. Caroline Badouel , Isabelle Chartrain , Joëlle Blot , Jean-Pierre Tassan |
2010-08-01 |
melk
|
| 17129738 |
A mitochondrial-targeting signal is present in the non-catalytic domain of the MELK protein kinase. Cell Biol. Int. Isabelle Chartrain , Joëlle Blot , Hubert Lerivray , Nicolas Guyot , Jean-Pierre Tassan |
2007-02-01 |
melk
|
| 16159311 |
Cell-cycle-dependent cortical localization of pEg3 protein kinase in Xenopus and human cells. Biol. Cell Isabelle Chartrain , Anne Couturier , Jean-Pierre Tassan |
2006-04-01 |
melk,
PEG3,
MELK
|
| 16628004 |
M-phase MELK activity is regulated by MPF and MAPK. Cell Cycle Caroline Badouel , Roman Körner , Marie Frank-Vaillant , Anne Couturier , Erich A Nigg , Jean-Pierre Tassan |
2006-04-01 | - |
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 12454917 |
Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Dev. Dyn. Steven L Klein , Robert L Strausberg , Lukas Wagner , Joan Pontius , Sandra W Clifton , Paul Richardson |
2002-12-01 |
Rpl28,
Uqcrc1,
cyp2a6,
cyp4b1.2,
cyp4b1,
LOC100036773,
cyp17a1,
cyp1a1,
mpst,
cct5b,
mlh1,
efha1,
cox7a2-b,
rraga,
wbp2,
aldh4a1,
usp3,
ints7,
nkiras1,
bbof1,
fam160b1,
emilin2,
gas7,
LOC100036792,
qsox1,
cacul1,
LOC100036795,
LOC100036796,
LOC100036797,
slc1a4,
tsga14,
LOC100036800,
xab2,
haus6,
LOC100036803,
taf5,
golph3l-b,
et-3,
mex3c,
plin1,
ttc7b,
diexf,
slc2a14,
tbc1d24.1,
il-8,
mrpl38,
cytl1,
LOC100036818,
sgf29,
LOC100036820,
dbib,
timm8b-b,
LOC100036823,
LOC100036824,
rgs1,
LOC100036826,
ndfip1,
LOC100036828,
LOC100036829,
admp2,
LOC100036831,
rasl10b,
mks1,
eif2d,
dcaf5,
gse1,
LOC100036837,
brd3,
rere,
csnk1g3,
pip4k2a,
tdrd5,
gpank1,
sin3b,
LOC100036845,
hk2,
kiz,
mob2.2,
ap1b1,
mfap3,
LOC100036851,
e2f1,
rpa2-b,
LOC100036854,
chtf8,
btn2a2,
lman2l,
h2afy,
LOC100036859,
LOC100036860,
tmem214-b,
cecr5,
rassf1,
LOC100036864,
LOC100036865,
dnase1l1,
aven,
nop2,
LOC100036869
|
| 11784115 |
Cell cycle regulation of pEg3, a new Xenopus protein kinase of the KIN1/PAR-1/MARK family. Dev. Biol. Joëlle Blot , Isabelle Chartrain , Christian Roghi , Michel Philippe , Jean-Pierre Tassan |
2002-01-15 |
melk
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员