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397827 xl64phr

397827

xl64phr

6-4 photolyase

protein-coding

Xenopus laevis

基因描述

Type Description
Definition 6-4 photolyase

研究结论

Date Results Publications
2019-08-10 11:02:00 A well-conserved arginine residue in Xenopus laevis (6-4)PL (Xl64) participates in DNA binding, through Coulomb and CH-pi interactions. 29762762
2017-10-21 11:54:00 photoreductive formation of FADH(-) through the Trp tetrad is essential for the biological function of the animal (6-4)PL 28880077
2017-05-13 13:43:00 A triple mutant is able to repair cyclobutane pyrimidine dimer (CPD) photoproduct, though the repair efficiency is 1 order of magnitude lower than that of wild-type. Repair spectra show lack of secondary structural alteration in the mutant, suggesting that the mutant gains substrate binding ability while it doesn't gain optimized conformational changes from light-induced electron transfer to release of the repaired DNA. 27431478
2016-06-11 10:51:00 the changed hydrogen bonding environments of C horizontal line O groups of (6-4) PP suggested restructuring of the binding pocket of the DNA lesion in the process of photoactivation. 26719910
2010-01-21 00:00:00 The carbonyl group of the 3' pyrimidone ring of Xenopus (6-4) photolyase plays an important role in the (6-4) photolyase repair mechanism. 19715341

名称对应

Type IDs
Gene
UniProtKB-ID: Q9I910_XENLA
UniprotKB: Q9I910
UniParc: UPI00000FC10C
EMBL: AB042255, BC169685, CM004478, BC169683
KO: xla:397827
Nucleutide sequences
EMBL-CDS: AAI69685.1, AAI69683.1, OCT72376.1, BAA97126.1
Gene_ORFName: XELAEV_18035355mg
Protein sequencees
RefSeq: NP_001081421.1
Others
UniRef100: UniRef100_Q9I910
UniRef90: UniRef90_Q9I910
UniRef50: UniRef50_Q9I911
UniGene: Xl.7198

全选

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研究热度

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