hes1.L - hes family bHLH transcription factor 1 L homeolog-BMKCloudï½ç¾è¿å®¢äº

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397813 hes1.L

基因描述

Type	Description
Definition	hes family bHLH transcription factor 1 L homeolog

研究结论

Date	Results	Publications
2019-11-02 11:20:00	In vitro, xHes1 protein can be phosphorylated by Cyclin-dependent-kinases. Under-phosphorylated xHes1 has enhanced inhibitory activity during neurogenesis. xHes1 reduces Ngn2 expression, protein stability and chromatin binding.	30600182

名称对应

Type	IDs
Synonymous	Xhairy-1, Xhairy1, Xlh1, hes-1, hes1, hes1-a, hes1-b
Gene	UniProtKB-ID: HES1A_XENLA, A0A1L8G9X1_XENLA UniprotKB: Q6IRB2, A0A1L8G9X1 UniParc: UPI000037602B EMBL: CM004474, BC070988, U36194 KO: xla:397813
Nucleutide sequences	EMBL-CDS: AAA79185.1, AAH70988.1, OCT80717.1 Gene_ORFName: XELAEV_18027531mg
Protein sequencees	RefSeq: NP_001081396.1
Others	UniRef100: UniRef100_Q6IRB2 UniRef90: UniRef90_Q6IRB2 UniRef50: UniRef50_P35428 UniGene: Xl.21817

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
30600182	N-terminal phosphorylation of xHes1 controls inhibition of primary neurogenesis in Xenopus. Biochem. Biophys. Res. Commun. Laura J A Hardwick , Anna Philpott	2019-02-05	-
17008450	Characterization and function of the bHLH-O protein XHes2: insight into the mechanisms controlling retinal cell fate decision. Development Marion SÃ¶lter , Morgane Locker , SÃ©bastien Boy , Vincent Taelman , Eric J Bellefroid , Muriel Perron , Tomas Pieler	2006-10-01	-
16818449	The Notch-effector HRT1 gene plays a role in glomerular development and patterning of the Xenopus pronephros anlagen. Development Vincent Taelman , Claude Van Campenhout , Marion SÃ¶lter , Tomas Pieler , Eric J Bellefroid	2006-08-01	-
15531363	Sequences downstream of the bHLH domain of the Xenopus hairy-related transcription factor-1 act as an extended dimerization domain that contributes to the selection of the partners. Dev. Biol. Vincent Taelman , RÃ©ginald Van Wayenbergh , Marion SÃ¶lter , Bruno Pichon , Tomas Pieler , Daniel Christophe , Eric J Bellefroid	2004-12-01	-
14648848	Identification of BOIP, a novel cDNA highly expressed during spermatogenesis that encodes a protein interacting with the orange domain of the hairy-related transcription factor HRT1/Hey1 in Xenopus and mouse. Dev. Dyn. Reginald Van Wayenbergh , Vincent Taelman , Bruno Pichon , Andreas Fischer , Sadia Kricha , Manfred Gessler , Daniel Christophe , Eric J Bellefroid	2003-12-01	Hey1, Ccdc89, zgc:172182, hes1-a, hes4-b, ccdc89, hey1, CCDC89
12477932	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team	2002-12-24	-
12454917	Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Dev. Dyn. Steven L Klein , Robert L Strausberg , Lukas Wagner , Joan Pontius , Sandra W Clifton , Paul Richardson	2002-12-01	Rpl28, Uqcrc1, cyp2a6, cyp4b1.2, cyp4b1, LOC100036773, cyp17a1, cyp1a1, mpst, cct5b, mlh1, efha1, cox7a2-b, rraga, wbp2, aldh4a1, usp3, ints7, nkiras1, bbof1, fam160b1, emilin2, gas7, LOC100036792, qsox1, cacul1, LOC100036795, LOC100036796, LOC100036797, slc1a4, tsga14, LOC100036800, xab2, haus6, LOC100036803, taf5, golph3l-b, et-3, mex3c, plin1, ttc7b, diexf, slc2a14, tbc1d24.1, il-8, mrpl38, cytl1, LOC100036818, sgf29, LOC100036820, dbib, timm8b-b, LOC100036823, LOC100036824, rgs1, LOC100036826, ndfip1, LOC100036828, LOC100036829, admp2, LOC100036831, rasl10b, mks1, eif2d, dcaf5, gse1, LOC100036837, brd3, rere, csnk1g3, pip4k2a, tdrd5, gpank1, sin3b, LOC100036845, hk2, kiz, mob2.2, ap1b1, mfap3, LOC100036851, e2f1, rpa2-b, LOC100036854, chtf8, btn2a2, lman2l, h2afy, LOC100036859, LOC100036860, tmem214-b, cecr5, rassf1, LOC100036864, LOC100036865, dnase1l1, aven, nop2, LOC100036869
11677053	Repression of XMyoD expression and myogenesis by Xhairy-1 in Xenopus early embryo. Mech. Dev. M Umbhauer , J C Boucaut , D L Shi	2001-11-01	-
8524259	Specificity for the hairy/enhancer of split basic helix-loop-helix (bHLH) proteins maps outside the bHLH domain and suggests two separable modes of transcriptional repression. Mol Cell Biol S R Dawson , D L Turner , H Weintraub , S M Parkhurst	1995-12-01	-

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