| Type | Description |
|---|---|
| Definition | LIF receptor alpha |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:30:00 | Leukemia inhibitory factor promotes gastric cancer cell proliferation, migration, and invasion via the LIFR-Hippo-YAP pathway. | 32827446 |
| 2020-12-19 13:44:00 | EGFR-upregulated LIFR promotes SUCLG2-dependent castration resistance and neuroendocrine differentiation of prostate cancer. | 32963351 |
| 2020-07-18 11:51:00 | Study in eight datasets from four public databases revealed that LIF was highly expressed while LIFR was lowly expressed in pancreatic adenocarcinoma (PAAD) tissues compared with adjacent or normal tissues. High LIF expression was associated with shorter overall survival whereas high LIFR expression was associated with longer overall survival confirming significance LIF and LIFR as biomarkers in PAAD. | 31854204 |
| 2020-02-15 11:00:00 | ERK2/LIFR/AKT axis modulates prostate carcinoma progression and offers a promising therapeutic and diagnostic target for prostate carcinoma | 30851421 |
| 2019-12-07 12:00:00 | The loss of LIFR protein was frequently found in Indian breast cancer patients, and aberrant promoter methylation showed a significant correlation with its downregulation. | 31557600 |
| Type | IDs |
|---|---|
| Synonymous | CD118, LIF-R, SJS2, STWS, SWS |
| Gene |
UniProtKB-ID:
LIFR_HUMAN,
A8K1Z4_HUMAN
UniprotKB:
P42702,
A8K1Z4
UniParc:
UPI00015DA594,
UPI000004CAC2
EMBL:
X61615,
U66563,
AK290059
Ensembl:
ENSG00000113594
KO:
hsa:3977
|
| Nucleutide sequences |
EMBL-CDS:
AAB61897.1,
CAA43805.1,
BAF82748.1
Ensembl_TRS:
ENST00000453190,
ENST00000263409
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000263409,
ENSP00000398368
RefSeq:
XP_011512344.1,
NP_001351226.1,
NP_001121143.1,
XP_016864952.1,
XP_016864951.1,
NP_002301.1,
NP_001351227.1
|
| Others |
UniRef100:
UniRef100_A8K1Z4,
UniRef100_P42702
UniRef90:
UniRef90_P42702
UniRef50:
UniRef50_P42702
UniGene:
Hs.133421
CCDS:
CCDS3927.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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