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397671 PPARG

397671

PPARG

peroxisome proliferator activated receptor gamma

protein-coding

Sus scrofa

基因描述

Type Description
Definition peroxisome proliferator activated receptor gamma

研究结论

Date Results Publications
2020-04-04 10:32:00 functionally distinct alleles of the PPARG gene are positioned in different parts of the cell nucleus. This confirms the importance of nuclear architecture to the regulation of PPARG gene transcription, and thus to the fate of the adipose cell. 30656515
2019-04-13 11:09:00 Study demonstrated that overexpression of DNMT3A promoted the expression of cell proliferation markers but significantly decreased the expression of p21 to repress cell proliferation by the methylation of p21 promoter. Moreover, overexpression of DNMT3A decreased lipid accumulation and significantly down-regulated the levels of adipogenic marker genes through the methylation of PPARg promoter. 30772521
2018-09-08 11:37:00 Our results provide novel insights into regulation of PPAR expression in ovarian follicles. We observed that FSH increased mRNA and protein expression of all PPARs isoforms, while LH only increased PPAR alpha and gamma. Steroids like progesterone and estradiol increased expression of PPAR alpha and gamma without affecting the beta isoform, while testosterone had no effect on all PPARs expression. 29550794
2018-05-05 12:03:00 The results of the present study suggested that PPARG may mediate porcine placental angiogenesis, by interfering with hypoxia inducible factor, vascular endothelial growth factor and angiopoietinmediated signaling. 28677792
2017-10-21 11:54:00 The results suggest the higher expression of miR-130a, which targeting peroxisome proliferator-activated receptor gamma, may be the reason for less fat deposition in intramuscular adipose tissue than subcutaneous adipose tissue. 28882569

名称对应

Type IDs
Gene
UniProtKB-ID: PPARG_PIG, Q6L9M5_PIG, A0A480EDI2_PIG
UniprotKB: O62807, Q6L9M5, A0A480EDI2
UniParc: UPI0000131FEF, UPI000002B176, UPI0006B15845
EMBL: DQIR01030069, AJ006757, AB097926, AB097927, AB097928, AJ006756, AF103946, AB097930, AB097929, AF059245, DQIR01110638
Ensembl: ENSSSCG00070016976, ENSSSCG00055010097, ENSSSCG00065034050
KO: ssc:397671
Nucleutide sequences
EMBL-CDS: CAA07224.1, CAA07225.1, AAD19577.1, BAD20646.1, AAC14348.1, BAD20645.1, BAD20643.1, BAD20642.1, BAD20644.1, HCZ85544.1, HDA66114.1
Ensembl_TRS: ENSSSCT00070033629, ENSSSCT00070033522, ENSSSCT00070033549, ENSSSCT00055019853, ENSSSCT00070033589, ENSSSCT00070033567, ENSSSCT00070033621, ENSSSCT00065046377
Protein sequencees
Ensembl_PRO: ENSSSCP00070028038, ENSSSCP00070027999, ENSSSCP00070028013, ENSSSCP00070028066, ENSSSCP00070028059, ENSSSCP00070028026, ENSSSCP00065019910, ENSSSCP00055015667
RefSeq: NP_999544.1, XP_005669845.3, XP_013837434.1, XP_013837435.1, XP_005669841.1, XP_005669840.1, XP_005669846.1, XP_013837436.1
Others
UniRef100: UniRef100_O62807, UniRef100_A0A480EDI2
UniRef90: UniRef90_O62807, UniRef90_P37231
UniRef50: UniRef50_O62807, UniRef50_P37231
UniGene: Ssc.14475

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